Moretti Rita, Torre Paola, Antonello Rodolfo M, Esposito Francesca, Bellini Giuseppe
Medicina Clinica, Ambulatorio Complicanze Internistiche Cerebrali, Dipartimento Universitario Clinici di Scienze Mediche Tecnologiche e Traslazionali, Università Degli Studi di Trieste, Ospedale di Cattinara, Strada Fiume 447, 34149 Trieste, Italy.
Curr Gerontol Geriatr Res. 2011;2011:263507. doi: 10.1155/2011/263507. Epub 2011 Mar 13.
Subcortical vascular dementia is a clinical entity, widespread, even challenging to diagnose and correctly treat. Patients with this diagnosis are old, frail, often with concomitant pathologies, and therefore, with many drugs in therapy. We tried to diagnose and follow up for three years more than 600 patients. Study subjects were men and women, not bedridden, aged 68-94 years, outpatients, recruited from June, 1st 2007 to June, 1st 2010. We examined them clinically, neurologically, with specific consideration on drug therapies. Our aim has been to define gait and imbalance problem, if eventually coexistent with the pathology of white matter and/or with the worsening of the deterioration. Drug intake interference has been detected and considered.
皮质下血管性痴呆是一种临床病症,广泛存在,甚至在诊断和正确治疗方面颇具挑战性。患有这种病症的患者年事已高、身体虚弱,常常伴有其他病症,因此正在接受多种药物治疗。我们对600多名患者进行了为期三年的诊断和随访。研究对象为68至94岁的非卧床男女门诊患者,于2007年6月1日至2010年6月1日招募。我们对他们进行了临床和神经学检查,并特别考虑了药物治疗情况。我们的目的是确定步态和平衡问题是否最终与白质病变和/或病情恶化同时存在。已检测并考虑了药物摄入干扰情况。