Department of Pharmacy, Uppsala University, Sweden.
Acta Derm Venereol. 2011 Jun;91(4):452-8. doi: 10.2340/00015555-1111.
Hand eczema is common and has an adverse impact on the lives of patients. There is a need for population-based surveys on the pharmacoepidemiological aspects, quality of life and impact of socioeconomic factors in hand eczema. The aim of this cross-sectional study was to investigate these factors. A questionnaire-based nationwide survey of health was performed, including questions on hand eczema, use of pharmaceuticals and socioeconomic factors. Quality of life was estimated with the generic instrument Short Form 36 (SF-36). The questionnaire was sent to 7,985 persons (age range 18-84 years), response rate 61.1% (n = 4,875). The 1-year prevalence of hand eczema in the study population was 7.5%. In this group, quality of life was lower. All dimensions of SF-36 were affected, most markedly general health and those dimensions reporting on mental health. In the group with self-reported hand eczema, 51% reported using topical pharmaceuticals. Hand eczema was more common among women (9.1%, n = 2,630) than among men (5.6%, n = 2,245) and in the age group below 65 years (8.5%, n = 3,274) compared with those aged 65 years and over (4.3%, n = 1,151). This survey clearly demonstrates the impact of hand eczema on several dimensions of life and also highlights age, gender and socioeconomic differences.
手部湿疹很常见，会对患者的生活造成不良影响。需要对人群中手部湿疹的药物流行病学方面、生活质量以及社会经济因素的影响进行基于人群的调查。本横断面研究旨在调查这些因素。我们进行了一项基于问卷调查的全国性健康调查，其中包括手部湿疹、药物使用和社会经济因素的问题。使用通用工具 Short Form 36（SF-36）评估生活质量。问卷发送给了 7985 人（年龄 18-84 岁），应答率为 61.1%（n=4875）。研究人群中手部湿疹的 1 年患病率为 7.5%。在该组中，生活质量较低。SF-36 的所有维度均受到影响，尤其是一般健康和心理健康相关维度。在自我报告手部湿疹的人群中，有 51%报告使用了局部药物。女性（9.1%，n=2630）比男性（5.6%，n=2245）以及 65 岁以下年龄组（8.5%，n=3274）更常见手部湿疹，而 65 岁及以上年龄组（4.3%，n=1151）则较少见。本调查清楚地表明了手部湿疹对生活的几个方面的影响，还突出了年龄、性别和社会经济差异。
