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经皮腔内血管成形术过程中并发的近段冠状动脉狭窄。

Late proximal coronary artery stenosis complicating percutaneous endovascular catheterisation procedures.

机构信息

Cardiovascular Center and Department of Anesthesiology, Taichung Veterans General Hospital, 160, Sec. 3, Chung-Kang Rd, Taichung, 40705, Taiwan.

出版信息

Neth Heart J. 2011 Sep;19(9):379-85. doi: 10.1007/s12471-011-0140-2.

Abstract

BACKGROUND

Late-onset proximal coronary artery stenosis caused by preceding percutaneous catheterisation procedures remains under-surveyed.

METHODS

From 1993, all patients undergoing percutaneous coronary procedures and a second session within 3 years were included except those ever treated by coronary bypass surgery or chest radiotherapy during this 3-year period. Emergence of a new lesion or worsening of an initially insignificant lesion to >50% of diameter stenosis at the never-treated ostial/proximal coronary segment on the follow-up angiogram was defined as late coronary stenosis caused by the previous catheterisation procedure and was analysed.

RESULTS

From January 1993 to December 2005, 3240 patients who underwent 5025 procedures met the inclusion criteria. Of them, 23 patients experienced an event of late coronary artery stenosis (overall incidence 0.46%), and interventional procedures, specifically shaped catheters (Voda, XB, Amplatz Left) and atherosclerosis vulnerability correlated with risks of adverse events. Most of these events could be managed by contemporary medical, interventional, or surgical strategies, yet hazards of mortality and long-term restenosis still existed from this catheter-induced complication.

CONCLUSIONS

Percutaneous catheterisation procedures could be complicated by late proximal coronary artery stenosis. Thus, when conducting these procedures, operators should select and manipulate catheters with caution, especially in patients with susceptible clinical characteristics.

摘要

背景

经皮冠状动脉介入治疗术后迟发性近段冠状动脉狭窄的研究较少。

方法

1993 年以来,除了在此 3 年内曾接受冠状动脉旁路手术或胸部放疗的患者外,所有接受经皮冠状动脉介入治疗且在 3 年内再次接受介入治疗的患者均被纳入研究。在随访血管造影中,从未治疗的开口/近段冠状动脉节段出现新病变或原有轻微病变进展至>50%直径狭窄定义为经皮冠状动脉介入治疗后迟发性冠状动脉狭窄,并对其进行分析。

结果

1993 年 1 月至 2005 年 12 月,5025 例患者符合纳入标准,共 3240 例。其中 23 例患者发生迟发性冠状动脉狭窄事件(总发生率为 0.46%),介入治疗,特别是特殊形状的导管(Voda、XB、Amplatz Left)和动脉粥样硬化易损性与不良事件风险相关。大多数这些事件可以通过现代的药物、介入或手术策略来治疗,但这种由导管引起的并发症仍存在死亡和长期再狭窄的风险。

结论

经皮冠状动脉介入治疗后可发生迟发性近段冠状动脉狭窄。因此,在进行这些治疗时,术者应谨慎选择和操作导管,尤其是在具有易患临床特征的患者中。

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