越南所产植物提取物的抗氧化/抗炎活性和总酚含量。

Antioxidant/anti-inflammatory activities and total phenolic content of extracts obtained from plants grown in Vietnam.

机构信息

Department of Environmental Toxicology, University of California, Davis, CA 95616, USA.

出版信息

J Sci Food Agric. 2011 Sep;91(12):2259-64. doi: 10.1002/jsfa.4448. Epub 2011 May 5.

DOI:10.1002/jsfa.4448

PMID:21547923

Abstract

BACKGROUND

Medicinal plants have been used to treat various diseases since ancient times. Their specific activities, such as antioxidant, anti-inflammatory and anti-cancer, have been studied intensively. In particular, plants grown in Vietnam have attracted considerable attention among food chemists as ideal sources of natural medicinal chemicals.

RESULTS

The methanol extracts from three edible Vietnamese-grown plants, Tram, Voi and Gac, tested with the DPPH assay showed antioxidant activities of 91.7 ± 0.4, 63.4 ± 0.7 and 3.7 ± 0.1% respectively. The malonaldehyde/gas chromatography assay also revealed strong antioxidant activity in Tram and Voi at a level of 25 µg mL(-1) (95.5 ± 0.3 and 78.5 ± 1.4% respectively). These results were confirmed by the thiobarbituric acid assay. The antioxidant activities correlated positively with the level of total phenolics in all plants. Tram exhibited dose response-related lipoxygenase-inhibitory activity, with values of 74.2 ± 3.1% at 5 µg mL(-1) , 62.0 ± 0% at 0.5 µg mL(-1) and 3.0 ± 1.5% at 0.05 µg mL(-1) . Conversely, Voi and Gac showed negative anti-lipoxygenase activity.

CONCLUSION

The antioxidant/anti-inflammatory activities and total phenolic contents of the three edible plants grown in Vietnam revealed that they are good sources of supplements for human health.

摘要

背景

自古以来，药用植物就被用于治疗各种疾病。它们的特定活性，如抗氧化、抗炎和抗癌，已经得到了深入研究。特别是在越南生长的植物，作为天然药用化学品的理想来源，引起了食品化学家的极大关注。

结果

用 DPPH 法测定，三种可食用的越南生长植物 Tram、Voi 和 Gac 的甲醇提取物的抗氧化活性分别为 91.7±0.4%、63.4±0.7%和 3.7±0.1%。丙二醛/气相色谱法也显示 Tram 和 Voi 在 25μgmL(-1)（分别为 95.5±0.3%和 78.5±1.4%）的水平下具有很强的抗氧化活性。这些结果通过硫代巴比妥酸法得到了证实。抗氧化活性与所有植物中的总酚含量呈正相关。Tram 表现出与剂量相关的脂氧合酶抑制活性，在 5μgmL(-1)时为 74.2±3.1%，在 0.5μgmL(-1)时为 62.0±0%，在 0.05μgmL(-1)时为 3.0±1.5%。相反，Voi 和 Gac 表现出负的抗脂氧合酶活性。