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青少年精索静脉曲张

Varicocele in adolescents.

作者信息

Dobanovacki Dusanka

出版信息

Med Pregl. 2010 Nov-Dec;63(11-12):741-6.

Abstract

Varicocele is the condition of abnormal venous dilatation of the pampiniform venous system presented at the upper pole of the testicle, sometimes associated with intratesticular varices. Dominantly presented on the left testicle, it is rarely noted on the right one or bilaterally. According to one interpretation, higher incidence in puberty can be accounted for by testicular blood flow increase in the testicular veins. Whatever the primary etiological factor may be, venous hypertension in the venous cord due to renospermatic venous reflux is a constant feature and is responsible for different pathological changes which occur in both the cord veins and the testicle. Vein congestion and heat exchange disturb and increase scrotal temperature having a negative effect on spermatogenesis and also induce irregular apoptosis in germ cells. Recently, reactive oxygen species production in association with decreased antioxidant capacity have been put under suspicion of deteriorating spermatogenesis. Varicoceles in adolescents are usually asymptomatic and the diagnosis is most frequently made according to the typical appearance by the routine annual school physical examination. Ultrasonography and Doppler mode are the most practical and non- invasive examinations. Semen analysis is possible three years after the onset of puberty when semen parameters reach adult values. Deterioration of spermatogenesis and infertility in adults could be accepted as a distant complication of adolescent varicocele. Many agree that indications for surgical intervention in adolescent are: pain, large varicoceles, hypotrophy of the involved testicle, bilateral varicocele, intratesticular varicocele and patients with abnormal semen parameters on serial evaluation. The ideal method for treating adolescent varicocele still remains controversial, but the main task is to decrease the number of recurrences and complications, while retaining optimum testicular function. Because of that, many surgeons respect the attitude "catch up growth".

摘要

精索静脉曲张是指蔓状静脉丛在睾丸上极出现异常静脉扩张的病症,有时伴有睾丸内静脉曲张。主要发生在左侧睾丸,右侧或双侧较少见。一种解释认为,青春期发病率较高是由于睾丸静脉内睾丸血流增加所致。无论主要病因是什么,肾精索静脉反流导致精索静脉内静脉高压是一个恒定特征,并且是精索静脉和睾丸中发生的不同病理变化的原因。静脉充血和热交换会干扰并升高阴囊温度,对精子发生产生负面影响,还会诱导生殖细胞发生不规则凋亡。最近,与抗氧化能力下降相关的活性氧生成被怀疑会恶化精子发生。青少年精索静脉曲张通常无症状,诊断最常根据常规年度学校体检中的典型表现做出。超声检查和多普勒模式是最实用且无创的检查方法。青春期开始三年后,当精液参数达到成人值时,可进行精液分析。成人精子发生恶化和不育可被视为青少年精索静脉曲张的远期并发症。许多人认为,青少年手术干预的指征包括:疼痛、大型精索静脉曲张、受累睾丸萎缩、双侧精索静脉曲张、睾丸内精索静脉曲张以及连续评估精液参数异常的患者。治疗青少年精索静脉曲张的理想方法仍存在争议,但主要任务是减少复发和并发症的数量,同时保留最佳睾丸功能。因此,许多外科医生秉持“追赶生长”的态度。

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