Palmer M L, De Risi D C, Pelikan A, Patel J, Nemoto T, Rosner D, Dao T L
Department of Breast Surgery, Roswell Park Memorial Institute, Buffalo, New York 14263.
Surg Gynecol Obstet. 1990 Mar;170(3):193-6.
The surgical treatment and outcome of 31 women with a pathologic diagnosis of cystosarcoma phyllodes at Roswell Park Memorial Institute were reviewed. Surgical excision was performed upon 20 patients with a mean tumor size of 4.5 centimeters (range of 1.0 to 9.0 centimeters). Mastectomy was performed initially upon 11 patients with a mean tumor size of 15 centimeters (range of 3 to 40 centimeters). Local recurrence was seen in five patients treated by excision and one patient treated by mastectomy. All patients retreated by repeat excisions were controlled; one patient retreated with mastectomy died with local recurrence and distant disease. Routine axillary dissections were not performed. Involvement of the axillary lymph nodes occurred in one patient and was associated with advanced systemic disease. Local recurrences did not imply associated systemic spread and were controlled in five of six patients by repeat excision or mastectomy. Although the benign behavior of this tumor is commonly emphasized, four of the patients we studied died of malignant spread of cystosarcoma phyllodes.
对罗斯韦尔帕克纪念研究所31例病理诊断为叶状囊肉瘤的女性患者的手术治疗及结果进行了回顾。对20例患者进行了手术切除，肿瘤平均大小为4.5厘米（范围为1.0至9.0厘米）。最初对11例患者进行了乳房切除术，肿瘤平均大小为15厘米（范围为3至40厘米）。接受切除治疗的5例患者和接受乳房切除术治疗的1例患者出现局部复发。所有通过重复切除进行再次治疗的患者病情均得到控制；1例接受乳房切除术再次治疗的患者死于局部复发和远处疾病。未进行常规腋窝清扫术。1例患者出现腋窝淋巴结受累，且与晚期全身疾病相关。局部复发并不意味着伴有全身扩散，6例患者中有5例通过重复切除或乳房切除术得到控制。尽管通常强调该肿瘤的良性行为，但我们研究的患者中有4例死于叶状囊肉瘤的恶性扩散。
