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内脏痛:脊髓传入纤维、肠嗜铬细胞、肠神经系统和应激。

Visceral pain: spinal afferents, enteric mast cells, enteric nervous system and stress.

机构信息

Department of Physiology & Cell Biology, The Ohio State University College of Medicine Columbus, Ohio 43210, USA.

出版信息

Curr Pharm Des. 2011;17(16):1573-5. doi: 10.2174/138161211796196918.

DOI:10.2174/138161211796196918
PMID:21548869
Abstract

This review aims to examine current basic and clinical concepts, the results of which are expanding our understanding of visceral hypersensitivity and functional abdominal pain of intestinal origin in relation to the enteric nervous system (ENS), spinal sensory neurons and enteric mast cells. Advances in this sphere are translating to improved insight into chronic functional abdominal and pelvic pain syndromes in general.

摘要

本次综述旨在探讨目前的基础和临床概念,这些研究结果加深了我们对于内脏高敏性和肠道来源的功能性腹痛与肠神经系统(ENS)、脊髓感觉神经元和肠嗜碱性粒细胞之间关系的理解。这一领域的进展有助于我们更好地了解一般的慢性功能性腹痛和盆腔疼痛综合征。

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