Vital A, Vital C, Rigal B, Decamps A, Emeriau J P, Galley P
Centre de Microscopie Electronique, Université de Bordeaux II, France.
Clin Neuropathol. 1990 Jan-Feb;9(1):10-5.
The superficial peroneal nerve from 46 elderly patients was studied by light and electron microscopy. Like most elderly people, these patients displayed evidence of varying degrees of peripheral nervous system dysfunction, but they were not suffering from any disease known to alter the peripheral nerve. A quantitative study showed that myelinated fiber loss predominated in the large diameter group. In the majority of cases, clusters of regenerating myelinated fibers were numerous. On the other hand, Wallerian-like degeneration aspects, segmental demyelination figures and axonal organelle accumulation were relatively rare. Unmyelinated fibers were also notably damaged in most cases. There was moderate reduplication of endoneurial vascular basement membrane.
对46例老年患者的腓浅神经进行了光镜和电镜研究。和大多数老年人一样，这些患者表现出不同程度的周围神经系统功能障碍的证据，但他们并未患有任何已知会改变周围神经的疾病。定量研究表明，有髓纤维丢失在大直径组中占主导。在大多数病例中，再生有髓纤维簇数量众多。另一方面，类华勒氏变性表现、节段性脱髓鞘图像和轴突细胞器聚集相对少见。在大多数病例中，无髓纤维也明显受损。神经内膜血管基底膜有中度重复。
