Department of Neurology, IRYCIS, Hospital Universitario Ramón y Cajal, Madrid, Spain.
J Neurol Neurosurg Psychiatry. 2011 Sep;82(9):981-5. doi: 10.1136/jnnp.2011.243709. Epub 2011 May 7.
Neurological problems are reported to be common in air travellers. The authors aimed to study neurological problems which might be associated with air traffic in a systematic way.
The authors analysed a prospective registry of all the patients referred from Madrid-Barajas International Airport to the emergency department of their tertiary university hospital (Hospital Universitario Ramón y Cajal), for whom a neurological consultation was required, during a period of 21 months.
77 patients with a history of air travel presented with neurological problems and were included in the analysis. Fifty-nine (76.6%) were male, and the mean age was 45.9 (range 8-89, SD 17.5). Onset of symptoms was after landing in 44 subjects (58.7%), during the flight in 31 (41.3%), and unknown in two (5.1%). Thirty-nine (50.9%) had seizures, 18 (23.4%) had a stroke, and 20 (26%) other diagnosis. Sixty-one per cent of the patients with seizures had no previous history of epilepsy. Seizures on presentation were significantly associated with the use of drugs (p = 0.0008), and most of the cases with known epilepsy admitted non-adherence to treatment. Three 'body packers' were admitted with seizures secondary to intra-abdominal cocaine pack rupture. Of eight ischaemic strokes, five had high-grade carotid stenosis, and one case had economy-class stroke syndrome. Six patients with stroke were eligible and treated with intravenous thrombolysis.
In our series of neurological problems among air travellers, drug-induced seizures and ischaemic strokes due to large-artery atherosclerosis were the commonest observed diagnoses.
据报道，航空旅行者常出现神经系统问题。作者旨在系统研究可能与航空交通相关的神经系统问题。
作者分析了马德里-巴拉哈斯国际机场将所有需要神经科会诊的患者转诊至其三级大学附属医院（拉蒙·卡哈尔大学医院）急诊科的前瞻性登记，在此期间，共 21 个月。
77 例有航空旅行史的患者出现神经系统问题并纳入分析。59 例（76.6%）为男性，平均年龄为 45.9 岁（范围 8-89，SD 17.5）。44 例（58.7%）患者症状在着陆后出现，31 例（41.3%）在飞行期间出现，2 例（5.1%）不明。39 例（50.9%）有癫痫发作，18 例（23.4%）有中风，20 例（26%）有其他诊断。61%的癫痫发作患者既往无癫痫病史。就诊时的癫痫发作与药物使用显著相关（p=0.0008），大多数已知癫痫的病例承认未遵医嘱服药。3 例“腹部藏毒者”因腹部可卡因包破裂导致癫痫发作入院。8 例缺血性中风中，5 例有颈动脉高度狭窄，1 例有经济舱综合征。6 例符合条件的中风患者接受了静脉溶栓治疗。
在我们的航空旅行者神经系统问题系列中，药物诱导的癫痫发作和大动脉粥样硬化引起的缺血性中风是最常见的观察到的诊断。
