Department of Anatomy and Neurobiology, Medical College of Pennsylvania, Philadelphia, PA 19129, USA Department of Cell Biology, Neurobiology and Anatomy, Ohio State University, 4072 Graves Hall, 333 West 10th Avenue, Columbus, OH, 43210-1239, USA.
Restor Neurol Neurosci. 1994 Jan 1;7(2):95-110. doi: 10.3233/RNN-1994-7205.
We used behavioral assessment techniques to investigate the recovery of locomotion after spinal cord injury. Complete hemisec-tions were made at T13 and LI in the cat spinal cord. Observational and high-speed kinematic analyses of bipedal treadmill and overground locomotion were made from 1 to 5 weeks postoperatively. Both bipedal and overground locomotion showed partial recovery. The early stage of recovery was characterized by an increased range of joint movement in a proximal to distal progression. During later stages, hindlimb movements became more complex and interjoint coordination markedly improved. Overground locomotion recovered faster and to a greater extent than bipedal locomotion, as indicated by the time course of recovery, joint angular excursions and intralimb coordination. We propose that the recovery of bipedal locomotion may be more limited by reorganization of segmenta) sensory systems than overground locomotion, perhaps because alternate strategies for overground locomotion are available.
我们使用行为评估技术来研究脊髓损伤后的运动功能恢复。在猫的脊髓 T13 和 L1 处进行完全半切。术后 1 至 5 周，对双足跑步机和地面行走进行观察和高速运动学分析。双足和地面行走均表现出部分恢复。恢复的早期阶段以关节运动从近端到远端的范围增加为特征。在后期，后肢运动变得更加复杂，关节间协调明显改善。与双足行走相比，地面行走的恢复更快，程度更大，这表现在恢复的时间过程、关节角度偏移和肢体间协调方面。我们提出，双足行走的恢复可能受到节段性感觉系统重组的限制比地面行走更大，这可能是因为替代地面行走的策略是可用的。
