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中度至重度创伤性脑损伤康复期间言语记忆编码和巩固缺陷的影响。

The impact of verbal memory encoding and consolidation deficits during recovery from moderate-to-severe traumatic brain injury.

机构信息

Department of Psychiatry/Psychology Division, Harbor-UCLA Medical Center, Torrance, California 90502, USA.

出版信息

J Head Trauma Rehabil. 2011 May-Jun;26(3):182-91. doi: 10.1097/HTR.0b013e318218dcf9.


DOI:10.1097/HTR.0b013e318218dcf9
PMID:21552067
Abstract

OBJECTIVE: Encoding and consolidation deficits appear to account for verbal memory impairment following traumatic brain injury (TBI). It is unknown whether these abilities vary during TBI recovery. We sought to determine the pattern and impact of verbal encoding and consolidation deficits following TBI. METHODS: Twenty-three participants with moderate-to-severe TBI and 25 age- and education-matched control participants' verbal memory abilities were assessed at 2 time points approximately 1 year apart; assessments occurred at acute and chronic visits for TBI survivors. MAIN OUTCOME MEASURES: Rey Auditory Verbal Learning Test and Item Specific Deficit Approach indices of encoding, consolidation, and retrieval deficits. RESULTS: In contrast to the controls, participants with TBI showed impaired verbal memory characterized by encoding and consolidation deficits at both time points. The TBI group's short-delayed recall and consolidation scores improved between the acute and chronic assessments. Encoding (primary) and consolidation (secondary) deficits emerged as predictors of acute and chronic recall in the TBI group. Also, acute visit encoding deficits predicted chronic visit delayed recall in TBI survivors, but acute consolidation deficits did not. CONCLUSIONS: These findings suggest that memory rehabilitation efforts focused on improving encoding of verbal material may be useful during both the acute and chronic phases of recovery following TBI.

摘要

目的:编码和巩固缺陷似乎是创伤性脑损伤 (TBI) 后言语记忆损伤的原因。目前尚不清楚这些能力在 TBI 恢复过程中是否会发生变化。我们试图确定 TBI 后言语编码和巩固缺陷的模式和影响。

方法:23 名中度至重度 TBI 患者和 25 名年龄和教育程度匹配的对照组参与者的言语记忆能力在大约 1 年的时间内进行了 2 次评估;对于 TBI 幸存者,评估分别在急性和慢性就诊时进行。

主要观察指标: Rey 听觉言语学习测试和项目特异性缺陷方法的编码、巩固和检索缺陷指数。

结果:与对照组相比,TBI 患者的言语记忆受损,在两个时间点均表现出编码和巩固缺陷。TBI 组的短延迟回忆和巩固评分在急性和慢性评估之间有所提高。编码(主要)和巩固(次要)缺陷成为 TBI 组急性和慢性回忆的预测因素。此外,急性就诊时的编码缺陷预测了 TBI 幸存者慢性就诊时的延迟回忆,但急性巩固缺陷则没有。

结论:这些发现表明,在 TBI 恢复的急性和慢性阶段,专注于改善言语材料编码的记忆康复努力可能是有用的。

相似文献

[1]
The impact of verbal memory encoding and consolidation deficits during recovery from moderate-to-severe traumatic brain injury.

J Head Trauma Rehabil. 2011

[2]
Effects of severe traumatic brain injury on visual memory.

J Clin Exp Neuropsychol. 2000-2

[3]
Verbal learning and memory deficits in traumatic brain injury: encoding, consolidation, and retrieval.

J Clin Exp Neuropsychol. 2001-4

[4]
Impact of pediatric traumatic brain injury on components of verbal memory.

J Clin Exp Neuropsychol. 1998-4

[5]
Impairments in learning, memory, and metamemory following childhood head injury.

J Head Trauma Rehabil. 2011

[6]
Acquisition versus retrieval deficits in traumatic brain injury: implications for memory rehabilitation.

Arch Phys Med Rehabil. 2000-10

[7]
Verbal learning patterns in moderate and severe traumatic brain injury.

J Clin Exp Neuropsychol. 1994-8

[8]
Exploring the roles of the executive and short-term feature-binding functions in retrieval of retrograde autobiographical memories in severe traumatic brain injury.

Cortex. 2010-8-3

[9]
[When do patients with traumatic brain injury lose verbal information? Implications for cognitive rehabilitation].

Rev Neurol. 2008

[10]
Working memory and new learning following pediatric traumatic brain injury.

Dev Neuropsychol. 2007

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[2]
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[3]
Effects of transcranial direct current stimulation (tDCS) and concurrent cognitive training on episodic memory in patients with traumatic brain injury: a double-blind, randomised, placebo-controlled study.

BMJ Open. 2021-8-26

[4]
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Mem Cognit. 2019-11

[5]
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[6]
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