Williams Travis J, Kershaw Allan D, Li Vincent, Wu Xinping
Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, Los Angeles, California 90089-1661, United States.
J Chem Educ. 2011 May 1;88(5):665-669. doi: 10.1021/ed1006822.
A convenient laboratory experiment is described in which NMR magnetization transfer by inversion recovery is used to measure the kinetics and thermochemistry of amide bond rotation. The experiment utilizes Varian spectrometers with the VNMRJ 2.3 software, but can be easily adapted to any NMR platform. The procedures and sample data sets in this article will enable instructors to use inversion recovery as a laboratory activity in applied NMR classes and provide research students with a convenient template with which to acquire inversion recovery data on research samples.
本文描述了一个便捷的实验室实验，其中通过反转恢复进行的核磁共振（NMR）磁化转移用于测量酰胺键旋转的动力学和热化学。该实验使用配备VNMRJ 2.3软件的瓦里安光谱仪，但可以轻松适配任何NMR平台。本文中的步骤和样本数据集将使教师能够在应用NMR课程中将反转恢复用作实验室活动，并为研究生提供一个便捷的模板，以便获取研究样本的反转恢复数据。
