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肾细胞癌孤立性脾转移:病例报告及文献复习

Isolated splenic metastasis from renal cell carcinoma: case report and review.

作者信息

Moir J A G, Sen G, Saif R, Haugk B, French J J

机构信息

Department of Hepatobiliary and Pancreatic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.

出版信息

Case Rep Gastroenterol. 2011 Apr 12;5(1):166-71. doi: 10.1159/000326963.

Abstract

This report presents the case of a 70-year-old woman with a previous history of a left nephrectomy for renal cell carcinoma (RCC), who developed general malaise and fatigue. Abdominal computed tomography demonstrated an enhancing 6 × 7 cm necrotic lesion in the lower pole of the spleen suggestive of a metastasis. Given the highly suspicious nature of the lesion we proceeded to splenectomy. The tumour did not breach the splenic capsule, and there was no local diaphragmatic involvement. The mass was concluded to be a true metastasis of the original RCC rather than local recurrence of the disease. The causes of isolated solid splenic lesions are wide and varied, however a past or present history of malignancy should lead to a high index of suspicion for a splenic metastasis. We report an extremely unusual case of spread from a RCC.

摘要

本报告介绍了一名70岁女性的病例,该患者既往因肾细胞癌(RCC)接受过左肾切除术,现出现全身不适和疲劳。腹部计算机断层扫描显示脾脏下极有一个6×7 cm的强化坏死病灶,提示转移。鉴于该病灶高度可疑,我们进行了脾切除术。肿瘤未突破脾包膜,也没有局部膈肌受累。该肿块被判定为原肾细胞癌的真正转移灶,而非疾病的局部复发。孤立性脾脏实性病变的病因广泛多样,然而,既往或目前有恶性肿瘤病史应高度怀疑脾转移。我们报告了一例肾细胞癌转移的极其罕见的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25de/3088742/35e6ec1292ca/crg0005-0166-f01.jpg

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