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肾细胞癌的脾和肺转移:一例报告

Splenic and pulmonary metastases from renal cell carcinoma: report of a case.

作者信息

Tatsuta M, Shiozaki K, Masutani S, Hashimoto K, Imamura H, Ikeda M, Miya A, Ishida H, Kawasaki T, Furukawa H, Satomi T, Hoshida Y

机构信息

Department of Surgery, Sakai Municipal Hospital, 1-1-1 Minamiyasui-cho, Sakai, Osaka 590-0064, Japan.

出版信息

Surg Today. 2001;31(5):463-5. doi: 10.1007/s005950170142.

Abstract

We report herein the case of a patient in whom pulmonary and splenic metastases from renal cell carcinoma (RCC) were successfully treated by surgical excision. A 69-year-old man who underwent left nephrectomy for RCC 17 months before was suspected to have a pulmonary metastasis based on computed tomography (CT) findings. Partial resection of the left lower lobe was performed with thoracoscopic assistance. However, 4 months later, a splenic tumor, 6 cm in diameter, was detected by CT and ultrasonography, and a splenectomy was performed. Histologically, both resected specimens were diagnosed as metastasis from RCC. A second pulmonary metastasis of the left upper lobe was resected 4 years 8 months later. The patient was in good health when last seen 11 months after his last operation. Malignant neoplasms rarely metastasize to the spleen and most cases are found at autopsy, or feature multiple distant metastases. Only four other cases of splenic metastases from RCC have been reported. The prognosis associated with splenic metastasis is favorable when only a solitary lesion exists.

摘要

我们在此报告一例肾细胞癌(RCC)肺和脾转移患者经手术切除成功治疗的病例。一名69岁男性,17个月前因RCC接受了左肾切除术,基于计算机断层扫描(CT)结果怀疑有肺转移。在胸腔镜辅助下进行了左下叶部分切除术。然而,4个月后,通过CT和超声检查发现了一个直径6 cm的脾肿瘤,并进行了脾切除术。组织学检查显示,两个切除标本均诊断为RCC转移。4年8个月后,切除了左上叶的第二次肺转移灶。在最后一次手术后11个月最后一次见到该患者时,他身体健康。恶性肿瘤很少转移至脾脏,大多数病例是在尸检时发现的,或具有多个远处转移。此前仅报道过另外4例RCC脾转移病例。当仅存在单个病灶时,与脾转移相关的预后良好。

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