Ndzengue Albert, Hammoudeh Fadi, Brutus Pierre, Ajah Ofem, Purcell Roland, Leadon Joseph, Rafal Richard B, Balmir Simon, Enriquez Danilo A, Posner Gerald L, Jaffe Eric A, Chandra Pradeep
Department of Medicine, Interfaith Medical Center, Brooklyn, N.Y., USA.
Case Rep Gastroenterol. 2011 Apr 13;5(1):223-6. doi: 10.1159/000326998.
Spontaneous liver bleeding is often reported in preeclampsia. It is otherwise rare and has been linked to gross anatomical lesions and coagulopathy. We report a case of subcapsular hematoma of the liver without any apparent lesion and in the absence of coagulopathy. A 41-year-old male, paraplegic for 16 years, presented to the emergency department 3 days after sudden onset of right upper quadrant and shoulder pain. He had been on vitamins and 5,000 units subcutaneous heparin 12-hourly at the nursing home for the last month. He was in no distress, afebrile, with stable vitals. Physical examination showed a diverting colostomy, tender hepatomegaly and sacral decubiti. A fecal occult blood test was negative. There was spastic paraplegia below the level of T12. Two days after admission, the patient was afebrile and hemodynamically stable. PTT, PT, liver profile, BUN and creatinine were all normal, however his hemoglobin had dropped from 11.3 to 7.6 g/dl. An abdominal CT scan revealed an isolated 9.0 × 1.8 cm subcapsular hematoma. The patient received blood transfusion in the intensive care unit and was discharged 7 days later. In conclusion, spontaneous liver hemorrhage occurs in the nonobstetrical population in the setting of gross anatomical lesions or coagulopathy. This is the first report of an isolated subcapsular liver hematoma.
子痫前期常出现自发性肝出血。在其他情况下则较为罕见,且与明显的解剖学病变和凝血病有关。我们报告一例无任何明显病变且无凝血病的肝包膜下血肿病例。一名41岁男性,截瘫16年,在突发右上腹和肩部疼痛3天后到急诊科就诊。过去一个月他在疗养院接受维生素治疗,并每12小时皮下注射5000单位肝素。他无痛苦,无发热,生命体征稳定。体格检查发现有转流性结肠造口术、肝肿大压痛和骶部褥疮。粪便潜血试验为阴性。胸12水平以下有痉挛性截瘫。入院两天后,患者无发热,血流动力学稳定。部分凝血活酶时间、凝血酶原时间、肝功能、尿素氮和肌酐均正常,然而他的血红蛋白已从11.3降至7.6 g/dl。腹部CT扫描显示一个孤立的9.0×1.8 cm肝包膜下血肿。患者在重症监护病房接受了输血治疗,7天后出院。总之,自发性肝出血发生在非产科人群中,与明显的解剖学病变或凝血病有关。这是首例孤立性肝包膜下血肿的报告。