National Institute of Education, Nanyang Technological University, Singapore, Singapore.
Analyst. 2011 Jun 21;136(12):2586-91. doi: 10.1039/c1an15280g. Epub 2011 May 9.
This paper reports a microchip with an integrated passive micromixer based on chaotic advection. The micromixer with staggered herringbone structures was used for luminol-peroxide chemiluminescence detection. The micromixer was examined to assess its suitability for chemiluminescence reaction. The relationship between the flow rate and the location of maximum chemiluminescence intensity was investigated. The light intensity was detected using an optical fiber attached along the mixing channel and a photon detector. A linear correlation between chemiluminescence intensity and the concentration of cobalt(ii) ions or hydrogen peroxide was observed. This microchip has a potential application in environmental monitoring for industries involved in heavy metals and in medical diagnostics.
本文报道了一种基于混沌对流的集成被动微混合器的微芯片。采用交错人字形结构的微混合器用于鲁米诺-过氧化物化学发光检测。评估了微混合器用于化学发光反应的适用性。研究了流速与最大化学发光强度位置之间的关系。通过沿混合通道附加光纤和光子探测器来检测光强度。观察到化学发光强度与钴（ii）离子或过氧化氢浓度之间存在线性相关性。这种微芯片在涉及重金属的工业环境监测和医学诊断中有潜在的应用。
