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[甲氨蝶呤成功治疗输卵管妊娠]

[Successful methotrexate therapy of tubal pregnancy].

作者信息

Güth U, Sartorius G, Obermann E C

机构信息

Frauenklinik, Universitätsspital Basel, Basel, Schweiz.

出版信息

Pathologe. 2011 Nov;32(6):514-6. doi: 10.1007/s00292-011-1429-z.

DOI:10.1007/s00292-011-1429-z
PMID:21553093
Abstract

Pathologists are well acquainted with the histopathologic features of a vital tubal pregnancy; however, tubal pregnancy successfully treated with medication is seen much less often, since these patients do not usually undergo surgery. We report a rare case of this type, in which no trophoblast tissue was found at histopathologic examination. Intratubal granulation tissue represented the remaining non-vital pregnancy tissue.

摘要

病理学家对活体内输卵管妊娠的组织病理学特征非常熟悉;然而,药物成功治疗的输卵管妊娠则少见得多,因为这些患者通常不接受手术。我们报告了1例罕见的此类病例,其组织病理学检查未发现滋养层组织。输卵管内肉芽组织代表剩余的非活性妊娠组织。

相似文献

1
[Successful methotrexate therapy of tubal pregnancy].[甲氨蝶呤成功治疗输卵管妊娠]
Pathologe. 2011 Nov;32(6):514-6. doi: 10.1007/s00292-011-1429-z.
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Effect of methotrexate on tubal epithelium. A report of three cases.甲氨蝶呤对输卵管上皮的影响。三例报告。
J Reprod Med. 1999 Jan;44(1):46-8.
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Predictors of methotrexate treatment failure in ectopic pregnancy.异位妊娠中甲氨蝶呤治疗失败的预测因素。
J Reprod Med. 2006 Feb;51(2):87-93.
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[Histopathologic findings of the trophoblast and tubal wall after medicamentous therapy of tubal pregnancies].
Geburtshilfe Frauenheilkd. 1995 Dec;55(12):671-3. doi: 10.1055/s-2007-1022311.
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[Pathophysiologic principles and clinical effects of local drug therapy of tubal pregnancies].输卵管妊娠局部药物治疗的病理生理原理及临床效果
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[Drug treatment of tubal pregnancy with methotrexate, with an analysis of 5 cases].[甲氨蝶呤药物治疗输卵管妊娠附5例分析]
Akush Ginekol (Sofiia). 2002;41(2):28-9.
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Low-dose methotrexate treatment for interstitial pregnancy. A case report.低剂量甲氨蝶呤治疗间质部妊娠。病例报告。
J Reprod Med. 2000 Feb;45(2):142-4.
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Chronic tubal ectopic pregnancy following clinically successful methotrexate treatment for an acute ectopic: a review of the literature.甲氨蝶呤治疗急性异位妊娠临床成功后发生的慢性输卵管异位妊娠:文献综述
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[Treatment of tubal pregnancy with methotrexate in gynecological clinic of MBAL-Pleven during five year period].[五年期间在普列文市MBAL妇科诊所采用甲氨蝶呤治疗输卵管妊娠]
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Histopathology of five tubes after treatment with methotrexate for a tubal pregnancy.五根输卵管在接受甲氨蝶呤治疗输卵管妊娠后的组织病理学表现。
Fertil Steril. 1992 Feb;57(2):341-5. doi: 10.1016/s0015-0282(16)54842-0.

本文引用的文献

1
Conservative management of tubal ectopic pregnancy.保守治疗输卵管妊娠。
Best Pract Res Clin Obstet Gynaecol. 2009 Aug;23(4):509-18. doi: 10.1016/j.bpobgyn.2008.12.007. Epub 2009 Mar 19.
2
Current evidence on surgery, systemic methotrexate and expectant management in the treatment of tubal ectopic pregnancy: a systematic review and meta-analysis.手术、全身应用甲氨蝶呤及期待疗法治疗输卵管异位妊娠的当前证据:一项系统评价和荟萃分析
Hum Reprod Update. 2008 Jul-Aug;14(4):309-19. doi: 10.1093/humupd/dmn012. Epub 2008 Jun 2.
3
Histopathologic findings in ectopic tubal pregnancy.
输卵管异位妊娠的组织病理学表现。
Int J Gynecol Pathol. 1989;8(3):255-62. doi: 10.1097/00004347-198909000-00009.