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糖尿病患者髋部骨折后的死亡率。

Mortality after hip fracture in diabetic patients.

作者信息

Gulcelik N E, Bayraktar M, Caglar O, Alpaslan M, Karakaya J

机构信息

Hacettepe Medical School, Department of Endocrinology and Metabolism, Sihhiye/Ankara, Turkey.

出版信息

Exp Clin Endocrinol Diabetes. 2011 Jul;119(7):414-8. doi: 10.1055/s-0030-1270466. Epub 2011 May 6.

Abstract

AIM

Type 2 diabetic patients have an increased incidence of hip fracture. In this study, we aimed to evaluate the mortality rate after hip fracture and determine the predictors of mortality in diabetic patients.

METHODS

356 patients who sustained a hip fracture between January 1997 and June 2008 were retrospectively reviewed for the study. Of the eligible 230 patients, 69 had type 2 diabetes. Each of these patients' medical and nursing notes were reviewed to ascertain additional information, including patient demographic factors, prior co-morbidities, fracture type, length of post-fracture stay and post-operative complications, the presence and duration of diabetes, glucose levels, HbA1c levels, albumin and hemoglobin levels.

RESULTS

148 women (64.3%) and 82 men (35.7%) were included in the study. The mean age of the study group was 76.1 ± 10.4 years. The mean age for diabetics was 76.1 ± 12.0 years and was 75.1 ± 9.4 years for non-diabetics ( P=0.343). Diabetic patients with hip fracture had a higher risk of mortality than the non-diabetic patients. One year survival probabilities of diabetic and non-diabetic patients were respectively 68.0% and 87.3% (p=0.033). In diabetic patients with a hip fracture, predictors of mortality were advanced age, the presence of postoperative complications and elevated HbA1c levels.

CONCLUSIONS

Diabetic patients have an increased risk of mortality after hip fracture. The medical care in the post-operative period, including glycemic control and postoperative complications, should be optimized in diabetic patients suffering from hip fracture in order to decrease mortality in these patients.

摘要

目的

2型糖尿病患者髋部骨折的发生率增加。在本研究中,我们旨在评估髋部骨折后的死亡率,并确定糖尿病患者死亡率的预测因素。

方法

回顾性分析1997年1月至2008年6月期间发生髋部骨折的356例患者。在符合条件的230例患者中,69例患有2型糖尿病。对这些患者的每份医疗和护理记录进行审查,以确定其他信息,包括患者人口统计学因素、既往合并症、骨折类型、骨折后住院时间和术后并发症、糖尿病的存在和持续时间、血糖水平、糖化血红蛋白水平、白蛋白和血红蛋白水平。

结果

本研究纳入148名女性(64.3%)和82名男性(35.7%)。研究组的平均年龄为76.1±10.4岁。糖尿病患者的平均年龄为76.1±12.0岁,非糖尿病患者为75.1±9.4岁(P=0.343)。髋部骨折的糖尿病患者比非糖尿病患者有更高的死亡风险。糖尿病和非糖尿病患者的一年生存率分别为68.0%和87.3%(p=0.033)。在髋部骨折的糖尿病患者中,死亡率的预测因素是高龄、术后并发症的存在和糖化血红蛋白水平升高。

结论

糖尿病患者髋部骨折后死亡风险增加。对于髋部骨折的糖尿病患者,应优化术后医疗护理,包括血糖控制和术后并发症,以降低这些患者的死亡率。

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