Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, United States.
Org Lett. 2011 Jun 3;13(11):2848-51. doi: 10.1021/ol200825j. Epub 2011 May 9.
The coupling of pentenylcarbene complexes and 2-alkynylbenzoyl derivatives affords naphthocycloheptanones in a single step involving simultaneous construction of both the seven-membered ring and one of the aromatic rings. Aryl tethered systems undergo intramolecular cyclopropanation.
戊烯基卡宾配合物与 2-炔基苯甲酰衍生物偶联,可一步合成同时构建七元环和一个芳环的萘并环庚酮。芳基连接体系发生分子内环丙化反应。