危重症维生素 D 缺乏患者有多缺乏？
How deficient are vitamin D deficient critically ill patients?
机构信息
Department of Diabetes and Endocrinology, Princess Alexandra Hospital, School of Medicine, University of Queensland, 199 Ipswich Road, Woolloongabba, Brisbane, Queensland, Australia 4102.
出版信息
Crit Care. 2011;15(2):154. doi: 10.1186/cc10126. Epub 2011 Apr 19.
Abstract
Vitamin D deficiency is highly prevalent among critically ill patients and may be associated with adverse outcomes. Failure of conventional vitamin D supplementation in correcting deficiency has called for studies to evaluate the efficacy and safety of a high-dose regime in critically ill patients. High-dose vitamin D supplementation that corrects a deficient state effectively and safely allows for intervention studies to be undertaken to determine the impact of vitamin D on morbidity and mortality in critically ill patients.
摘要
维生素 D 缺乏在危重症患者中非常普遍，可能与不良结局有关。常规维生素 D 补充未能纠正缺乏症，因此需要研究评估高剂量方案在危重症患者中的疗效和安全性。有效且安全地纠正缺乏状态的高剂量维生素 D 补充允许进行干预研究，以确定维生素 D 对危重症患者发病率和死亡率的影响。
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