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波兰婴幼儿配方奶粉中的氟化物饮食摄入量。

Dietary fluoride intake from infant and toddler formulas in Poland.

机构信息

Department of Pediatric Dentistry, Poznan University of Medical Sciences, Poznan, Poland.

出版信息

Food Chem Toxicol. 2011 Aug;49(8):1759-63. doi: 10.1016/j.fct.2011.04.023. Epub 2011 Apr 27.

Abstract

Risk of enamel fluorosis associated with excessive fluoride intake during infancy and early childhood has been widely reported in literature. Results of several studies indicate that infant formula consumption, especially in the form of powdered concentrate, may appreciably increase children's fluoride exposure in optimally fluoridated communities. The aim of the study was to measure fluoride content of infant and toddler formulas available in Poland and to discuss implications of the results. Twenty nine brands of powdered formulas were evaluated. Analyzes were performed with the use of ionselective fluoride electrode (09-37 type) and a RAE 111 chloride-silver reference electrode (MARAT). Results revealed that concentration of fluoride in all products was low (mean 29.0 μg/100 g), and that the formula itself is not a significant source of fluoride exposure. However, when reconstituted with water containing more than 0.5 ppm of fluoride, starting formulas and follow-on formulas may provide a daily fluoride intake of above the suggested threshold for fluorosis. Thus, fully formula-fed infants consuming mother milk substitutes prepared with optimally fluoridated water may be at increased risk of dental fluorosis.

摘要

已有大量文献报道,婴幼儿时期摄入过量氟化物会导致氟斑牙风险增加。一些研究结果表明,婴幼儿配方奶粉的摄入,尤其是以粉状浓缩物形式摄入,可能会显著增加在氟化物含量适宜的社区中儿童的氟暴露。本研究旨在测量波兰市售婴幼儿配方奶粉中的氟含量,并讨论其结果的意义。评估了 29 种品牌的粉状配方奶粉。使用离子选择性氟电极(09-37 型)和 RAE 111 氯化银参比电极(MARAT)进行分析。结果表明,所有产品中的氟浓度均较低(平均值为 29.0μg/100g),且配方本身并不是氟化物暴露的重要来源。然而,当用氟化物含量超过 0.5ppm 的水冲调时,起始配方和后续配方可能会提供超过氟斑牙建议阈值的每日氟化物摄入量。因此,完全以配方奶喂养且用含氟量适宜的水冲调代乳品的婴儿可能会增加患氟斑牙的风险。

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