Pagliari Ana Valéria, Moimaz Suzely Adas Saliba, Saliba Orlando, Delbem Alberto Carlos Botazzo, Sassaki Kikue Takebayashi
School of Dentistry of Araçatuba, São Paulo State University.
Braz Oral Res. 2006 Jul-Sep;20(3):269-74. doi: 10.1590/s1806-83242006000300016.
The aim of the present study was to determine the fluoride concentration in some brands of mother's milk substitutes and evaluate the possibility of developing dental fluorosis by consuming these products. The products, all powdered, were divided into 3 groups: infant formulae (group I, n = 7), milk-based (group M, n = 8) and soy-based (group S, n = 3). Samples from 3 cans of different batches of each brand were reconstituted in deionized water and analyzed using the specific electrode method, after hexamethyldisiloxane (HMDS) facilitated diffusion. The fluoride content (mg F/L) of the products ranged from 0.044 to 0.326 (I), 0.014 to 0.045 (M) and 0.253 to 0.702 (S). There was significant difference in the fluoride content of cans from distinct batches (p < 0.05) in most of the brands. The reconstitution of all products in water with optimal fluoride concentration for consumption during the mineralization phase of the primary teeth could result in daily fluoride intake above 0.07 mg F/kg body weight/day. Therefore, the consumption of these products, especially when reconstituted with optimally fluoridated water, could increase the risk of developing dental fluorosis.
本研究的目的是测定某些品牌母乳代用品中的氟化物浓度,并评估食用这些产品导致氟斑牙的可能性。这些产品均为粉末状,分为3组:婴儿配方奶粉(I组,n = 7)、牛奶基产品(M组,n = 8)和大豆基产品(S组,n = 3)。每个品牌不同批次的3罐样品用去离子水复溶,在六甲基二硅氧烷(HMDS)促进扩散后,采用特定电极法进行分析。产品的氟含量(mg F/L)范围为0.044至0.326(I组)、0.014至0.045(M组)和0.253至0.702(S组)。大多数品牌不同批次罐装产品的氟含量存在显著差异(p < 0.05)。在乳牙矿化阶段,将所有产品用氟浓度适宜的水复溶后食用,可能导致每日氟摄入量超过0.07 mg F/kg体重/天。因此,食用这些产品,尤其是用氟化物浓度适宜的水复溶后食用,可能会增加患氟斑牙的风险。