San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA 92123, USA.
Brain Behav Immun. 2011 Aug;25(6):1256-63. doi: 10.1016/j.bbi.2011.04.016. Epub 2011 May 1.
Anger and hostility are psychological factors that appear to play a salient role in relation to cardiovascular disease (CVD) risk; however, their association with risk within the Latino population remains relatively unexplored. The current study examined associations between overall trait anger, anger subdimensions (i.e., anger temperament and anger reaction) and cynical hostility with sICAM-1, a marker of cellular adhesion and systemic inflammation related to CVD risk, in a sample of 294 middleaged Mexican-American women. Results showed no association between trait anger or anger temperament and sICAM-1. Anger reaction was marginally associated with sICAM-1 (β=4.77, p=.06). Cynical hostility was significantly associated with sICAM-1 (β=5.89, p=.04) even after controlling for demographic, biological and behavioral covariates. The current study provides evidence that specific aspects of anger and hostility relate to physiological pathways that potentially influence CVD risk. Findings are discussed in light of contextual cultural factors.
愤怒和敌意是心理因素，似乎在心血管疾病（CVD）风险中起着重要作用；然而，它们与拉丁裔人群风险之间的关系仍相对未得到探索。本研究在 294 名中年墨西哥裔美国女性样本中，检查了总体特质愤怒、愤怒亚维度（即愤怒气质和愤怒反应）以及玩世不恭的敌意与 sICAM-1 之间的关联，sICAM-1 是一种与 CVD 风险相关的细胞黏附和全身炎症的标志物。结果显示，特质愤怒或愤怒气质与 sICAM-1 之间没有关联。愤怒反应与 sICAM-1 呈边缘相关（β=4.77，p=.06）。即使在控制人口统计学、生物学和行为学协变量后，玩世不恭的敌意仍与 sICAM-1 显著相关（β=5.89，p=.04）。本研究提供了证据，表明愤怒和敌意的特定方面与潜在影响 CVD 风险的生理途径有关。研究结果结合背景文化因素进行了讨论。
