溶剂控制的金(III)催化、杂环化引发的 Nazarov 反应的机理二分法。
Solvent controlled mechanistic dichotomy in a Au(III)-catalyzed, heterocyclization triggered, Nazarov reaction.
机构信息
Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA.
出版信息
Chem Commun (Camb). 2011 Jun 21;47(23):6707-9. doi: 10.1039/c1cc10920k. Epub 2011 May 10.
PMID:21556413
Abstract
Tandem Au(III)-catalyzed heterocyclization/Nazarov cyclizations leading to substituted carbocycle fused furans are described. An interesting dichotomy of reaction pathways as a function of solvent, confirmed by the isolation and trapping of reaction intermediates, provided a basis for computational studies that supported the experimental findings.
摘要
串联 Au(III)-催化杂环化/Nazarov 环化反应，生成取代的碳环稠合呋喃，本文对此进行了描述。通过分离和捕获反应中间体，证实了溶剂对反应途径的有趣二分法，这为支持实验结果的计算研究提供了基础。
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