University of California at Los Angeles Stroke Center, UCLA Medical Center, Los Angeles, CA 90095, USA.
Neurotherapeutics. 2011 Jul;8(3):330-9. doi: 10.1007/s13311-011-0046-0.
Stroke, whether hemorrhagic or ischemic in nature, has the ability to lead to devastating and debilitating patient outcomes, which not only has direct implications from a healthcare standpoint, but its effects are longstanding and they impact the community as a whole. For decades, the goal of advancement and refinement in imaging modalities has been to develop the most precise, convenient, widely available and reproducible interpretable modality for the detection of stroke, not only in its hyperacute phase, but a method to be able to predict its evolution through the natural course of disease. Diagnosis is one of the most important initial roles, which imaging fulfills after the identification of existent pathology. However, imaging fulfills an even more important goal by using a combination of imaging modalities and their precise interpretation, which lends itself to understanding the mechanisms and pathophysiology of underlying disease, and therefore guides therapeutic decision-making in a patient-tailored fashion. This review explores the most commonly used brain imaging modalities, computer tomography, and magnetic resonance imaging, with an aim to demonstrate their dynamic use in uncovering stroke mechanism, facilitating prognostication, and potentially guiding therapy.
中风，无论是出血性还是缺血性，都有导致灾难性和使人衰弱的患者结局的能力，这不仅直接影响到医疗保健方面，而且其影响是长期的，并影响整个社区。几十年来，成像方式的进步和完善的目标一直是开发最精确、最方便、最广泛可用和可重复的可解释方式，以检测中风，不仅在其超急性期，而且能够通过疾病的自然过程来预测其演变。诊断是最重要的初始角色之一，在确定存在的病理学后，影像学可以实现这一角色。然而，影像学通过使用成像方式的组合及其精确解释来实现更重要的目标，这有助于理解潜在疾病的机制和病理生理学，从而以患者为中心的方式指导治疗决策。本综述探讨了最常用的脑成像方式，即计算机断层扫描和磁共振成像，旨在展示它们在揭示中风机制、促进预后和潜在指导治疗方面的动态应用。
