Servicio de Radiología, Fundación Instituto Valenciano de Oncología, C/ Beltrán Báguena 19, Valencia, Spain.
Spine J. 2011 May;11(5):402-11. doi: 10.1016/j.spinee.2011.03.019.
Conflicting reports exist regarding the prevalence of Modic changes among low back pain (LBP) patients and factors associated with their existence.
To assess the prevalence of Modic changes and other findings on lumbar magnetic resonance imaging (MRI) among Spanish adult chronic LBP patients and the patient characteristics and radiological findings associated with Modic changes.
A cross-sectional imaging study among chronic LBP patients.
Four hundred eighty-seven patients (263 women and 224 men) undergoing lumbar spine MRI examination for chronic LBP.
Gender, age, body mass index (BMI), lifetime smoking exposure, degree of physical activity, and image features (disc degeneration, type and extension of Modic changes, disc contour, annular tears, spinal stenosis, and spondylolisthesis).
Ten radiologists from six hospitals across six cities in Spain consecutively recruited adult patients in whom lumbar MRI had been prescribed for LBP lasting ≥3 months. Patients' characteristics and imaging findings were assessed through previously validated instruments. A multivariate logistic regression model was developed to assess the features associated with Modic changes.
Modic changes were found in 81% of the patients. The most common was Type II (51.3%), affecting only the end plate. Variables associated with Type I changes were disc contour abnormalities, spondylolisthesis, and disc degeneration. The same variables were associated with a higher risk of Type II or any type of Modic changes, as well as being male, and having a higher BMI.
Modic changes are found in 81% (95% confidence interval, 77-85) of adult Spanish patients in whom an MRI is prescribed for chronic LBP. Modic changes are more likely to be found in males with a high BMI, who also show disc contour abnormalities, spondylolisthesis, or disc degeneration.
关于患有下腰痛（LBP）的患者中 Modic 改变的流行情况以及与这些改变存在相关的因素，存在相互矛盾的报告。
评估西班牙成年慢性 LBP 患者腰椎磁共振成像（MRI）中 Modic 改变和其他发现的流行情况，以及与 Modic 改变相关的患者特征和放射学发现。
一项慢性 LBP 患者的横断面影像学研究。
487 例（263 名女性和 224 名男性）因慢性 LBP 接受腰椎 MRI 检查的患者。
性别、年龄、体重指数（BMI）、终生吸烟暴露、身体活动程度以及影像学特征（椎间盘退变、Modic 改变的类型和程度、椎间盘轮廓、环形撕裂、椎管狭窄和脊椎滑脱）。
来自西班牙六个城市的六家医院的十位放射科医生连续招募了因慢性 LBP 持续≥3 个月而接受腰椎 MRI 检查的成年患者。通过先前验证的工具评估患者的特征和影像学发现。采用多变量逻辑回归模型评估与 Modic 改变相关的特征。
81%的患者存在 Modic 改变。最常见的是 II 型（51.3%），仅影响终板。与 I 型改变相关的变量是椎间盘轮廓异常、脊椎滑脱和椎间盘退变。相同的变量与 II 型或任何类型的 Modic 改变的风险增加相关，以及男性、较高的 BMI。
在因慢性 LBP 而接受 MRI 检查的西班牙成年患者中，81%（95%置信区间，77-85）存在 Modic 改变。Modic 改变更可能发生在 BMI 较高的男性中，他们还表现出椎间盘轮廓异常、脊椎滑脱或椎间盘退变。
