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选择临床医生在为患有亚急性和慢性非恶性疼痛的青少年使用阿片类药物方面的执业行为。

Select practice behaviors of clinicians on the use of opioids for adolescents with subacute and chronic nonmalignant pain.

作者信息

Saroyan John M, Cheng Wendy Y, Taylor Damani C, Afzal Amna, Sonty Nomita, Sullivan Maria A

机构信息

Department of Anesthesiology, Columbia University College of Physicians and Surgeons, New York, New York, USA.

出版信息

J Opioid Manag. 2011 Mar-Apr;7(2):123-34. doi: 10.5055/jom.2011.0055.

Abstract

OBJECTIVES

To characterize the opioid prescribing and monitoring practices of providers for chronic nonmalignant pain (CNP) and subacute postoperative pain (SAPOP) in adolescents.

DESIGN

Web-based cross-sectional self-report survey.

SETTING

Free-standing pediatric tertiary academic center.

PARTICIPANTS

A total of 183 physicians and nurse practitioners were eligible. Of 115 (62.8 percent) participants who responded, 108 (93.9 percent) completed the survey.

MAIN OUTCOME MEASURES

Self-reported frequency of opioid prescription for SAPOP and CNP conditions and frequency of associated monitoring practices.

RESULTS

For 10 of the 13 pain conditions included, some participants endorsed "monthly or more opioid prescriptions" while others endorsed "opioids do not represent appropriate management." Opioid prescribing is present for almost all pain conditions but is substantially more common for nonacute vaso-occlusive-related sickle cell disease, scoliosis correction, and video-assisted pectus excavatum-related pains. When compared with the reference group, CNP with no identifiable pathology, the odds ratio (OR) of an opioid being prescribed for CNP states with identifiable pathology was not significantly higher. The OR for SAPOP was significantly higher (p < 0.0001). None of the opioid prescribers reported collecting urine toxicology before or during opioid therapy.

CONCLUSIONS

This survey identifies a diversity of self-reported clinician opioid prescribing practices for adolescents with CNP and SAPOP. Urine collection for drug toxicology screening is not utilized by opioid prescribers. Surveys of similar clinician practice behaviors at other institutions are warranted to replicate this finding and to establish common clinicalpractice for usage and monitoring of opioids in conditions where guidelines do not yet exist.

摘要

目的

描述青少年慢性非恶性疼痛(CNP)和亚急性术后疼痛(SAPOP)提供者的阿片类药物处方及监测实践。

设计

基于网络的横断面自我报告调查。

地点

独立的儿科三级学术中心。

参与者

共有183名医生和执业护士符合条件。在115名(62.8%)回复的参与者中,108名(93.9%)完成了调查。

主要观察指标

自我报告的SAPOP和CNP情况下阿片类药物处方频率以及相关监测实践频率。

结果

在所纳入的13种疼痛情况中的10种,一些参与者认可“每月或更频繁的阿片类药物处方”,而另一些参与者则认可“阿片类药物并非合适的治疗方法”。几乎所有疼痛情况都有阿片类药物处方,但在非急性血管闭塞相关镰状细胞病、脊柱侧弯矫正以及电视辅助漏斗胸相关疼痛中更为常见。与无明确病理的CNP参考组相比,有明确病理的CNP状态开具阿片类药物的比值比(OR)并无显著升高。SAPOP的OR显著更高(p < 0.0001)。没有阿片类药物处方者报告在阿片类药物治疗前或治疗期间收集尿液进行毒理学检测。

结论

本调查发现,对于患有CNP和SAPOP的青少年,临床医生自我报告的阿片类药物处方实践存在多样性。阿片类药物处方者未采用尿液收集进行药物毒理学筛查。有必要对其他机构类似的临床医生实践行为进行调查,以重复这一发现,并在尚无指南的情况下确立阿片类药物使用和监测的常见临床实践。

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