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颅内破裂动脉瘤合并动静脉畸形的血管内治疗:14例出血病例的临床分析

Endovascular treatment of intracranial ruptured aneurysms associated with arteriovenous malformations: a clinical analysis of 14 hemorrhagic cases.

作者信息

Yu J-L, Yang S, Luo Q, Wang H-L, Wang B, Qu Y-Y, Xu K

机构信息

Department of Neurosurgery, First Hospital of Jilin University, Changchun, Jilin Province, China.

出版信息

Interv Neuroradiol. 2011 Mar;17(1):78-86. doi: 10.1177/159101991101700113. Epub 2011 Apr 29.

Abstract

This study investigated and summarized endovascular therapeutic strategies for intracranial ruptured aneurysms associated with arteriovenous malformations (AVMs). Between June 2005 and June 2009, we identified 16 aneurysms in 14 hemorrhagic cases of intracranial AVM using digital subtraction angiography (DSA). Of the 16 aneurysms, 14 were ruptured and two were unruptured. Aneurysms were classified as types I to IV, and were treated. Aneurysm treatment was followed by AVM treatment via various therapies, including embolization, gamma knife radiotherapy, or follow-up and observation to reduce the risk of aneurysm rupture or intracranial hemorrhage. Over a follow-up period ranging from six months to one year, none of the patients had aneurysm ruptures or intracranial hemorrhage. Most (13/14) patients had a Glasgow Outcome Scale (GOS) score of 5, and one patient had a score of 4. Sixteen aneurysms were treated successfully, as confirmed by DSA examination, and no AVMs re-grew. Clinical therapeutic strategies for intracranial ruptured aneurysms associated with AVMs should include aneurysm treatment first to reduce the risk of rupture and intracranial hemorrhage, eventually leading to a better prognosis.

摘要

本研究调查并总结了与动静脉畸形(AVM)相关的颅内破裂动脉瘤的血管内治疗策略。2005年6月至2009年6月期间,我们通过数字减影血管造影(DSA)在14例颅内AVM出血病例中发现了16个动脉瘤。在这16个动脉瘤中,14个为破裂动脉瘤,2个为未破裂动脉瘤。动脉瘤被分为I至IV型,并进行了治疗。动脉瘤治疗后,通过包括栓塞、伽玛刀放疗或随访观察等各种疗法对AVM进行治疗,以降低动脉瘤破裂或颅内出血的风险。在6个月至1年的随访期内,没有患者发生动脉瘤破裂或颅内出血。大多数(13/14)患者的格拉斯哥预后量表(GOS)评分为5分,1例患者评分为4分。经DSA检查证实,16个动脉瘤均成功治疗,且没有AVM复发。与AVM相关的颅内破裂动脉瘤的临床治疗策略应首先进行动脉瘤治疗,以降低破裂和颅内出血的风险,最终获得更好的预后。

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