Larsen Mette Vang, Karstoft Kristian, Andersen Mette Klarskov
Infektionsmedicinsk Afdeling, Hvidovre Hospital, 2650 Hvidovre, Denmark.
Ugeskr Laeger. 2011 May 9;173(19):1363-4.
A 22-year-old man presented with severe back pain and 60% eosinophilia after returning from the tropics. An extensive investigation for parasitic diseases was negative. Over time, his haemoglobin level and thrombocyte count fell, and the spleen and several lymph nodes were enlarged. The patient was diagnosed with acute lymphatic leukaemia with eosinophilia by bone marrow microscopy and flow cytometry. Chromosome analysis detected clonal abnormalities including t(5;14)(q31;q32). He initially responded to chemotherapy, but due to residual disease, he now awaits allogeneic bone marrow transplantation.
一名22岁男子从热带地区返回后出现严重背痛和60%的嗜酸性粒细胞增多。对寄生虫病进行的广泛检查结果为阴性。随着时间的推移，他的血红蛋白水平和血小板计数下降，脾脏和多个淋巴结肿大。通过骨髓显微镜检查和流式细胞术，该患者被诊断为伴有嗜酸性粒细胞增多的急性淋巴细胞白血病。染色体分析检测到包括t(5;14)(q31;q32)在内的克隆异常。他最初对化疗有反应，但由于残留疾病，他现在等待异基因骨髓移植。
