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一项关于耳瘢痕疙瘩压缩治疗的初步研究结果令人鼓舞。

Promising results from a pilot study on compression treatment of ear keloids.

机构信息

German Cancer Research Center, Heidelberg, Germany.

出版信息

J Cutan Med Surg. 2011 May-Jun;15(3):130-6. doi: 10.2310/7750.2011.10015.

DOI:10.2310/7750.2011.10015
PMID:21561580
Abstract

BACKGROUND

Ear keloids continue to be a therapeutic challenge.

OBJECTIVE

To evaluate the clinical success of a modified "oyster splint technique."

METHODS

Ten patients with an ear keloid agreed to receive the compression therapy. After surgical removal, a compressive device made of acrylic resin was applied on top of a silicone gel sheet and patients were asked to wear the splint 23 hours a day for at least 8 months. If the scar showed a tendency to grow, corticosteroids were injected intralesionally. In addition to recurrence rate, other parameters and wearing times were obtained by an interview.

RESULTS

Two of 10 patients experienced a recurrence in a mean follow-up period of 18.2 months (range 4-44 months). The daily wearing time of the compression splint was critical for the success of the treatment (p = .022). The splint had to be worn at least 10 hours a day for a minimum of 8 months to prevent recurrence. However, the need for additional intralesional steroid injections was significantly lower in patients wearing the splint for more than 20 hours per day (p = .048). The splint treatment was painless for 80% of patients. The therapeutic result was given a median mark of 1.75 (1 =   best, 6 = worst).

CONCLUSION

Although it requires considerable time and effort, the technique seems to be a promising therapy.

摘要

背景

耳部瘢痕疙瘩仍然是一种治疗挑战。

目的

评估改良“牡蛎夹板技术”的临床疗效。

方法

10 名耳部瘢痕疙瘩患者同意接受压迫治疗。在手术切除后,在硅凝胶片上应用丙烯酸树脂制成的压缩装置,并要求患者每天佩戴夹板 23 小时,至少 8 个月。如果瘢痕有生长趋势,则进行皮损内注射皮质类固醇。除复发率外,还通过访谈获得其他参数和佩戴时间。

结果

10 名患者中有 2 名在平均 18.2 个月(4-44 个月)的随访期内复发。压缩夹板的日佩戴时间对治疗的成功至关重要(p =.022)。为了防止复发,夹板必须每天佩戴至少 10 小时,至少 8 个月。然而,每天佩戴夹板超过 20 小时的患者需要额外皮损内注射皮质类固醇的次数明显更低(p =.048)。80%的患者对夹板治疗无疼痛感。治疗效果的中位数评分为 1.75(1=最佳,6=最差)。

结论

尽管需要相当多的时间和精力,但该技术似乎是一种有前途的治疗方法。

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