Department of Neurology, Reinier De Graaf Group, Delft, the Netherlands.
Epileptic Disord. 2011 Jun;13(2):185-7. doi: 10.1684/epd.2011.0424.
Malignant migrating partial seizures in infancy is an epilepsy syndrome characterised by an onset before the age of six months, multifocal seizures and an EEG pattern consisting of seizures which occur independently and sequentially from both hemispheres. The clinical course of a four-month-old boy with this syndrome, illustrated by video material of the seizures and EEG recordings, is described. The possible neurophysiological mechanism of epileptogenic activity alternating or 'migrating' from one hemisphere to the other is discussed.
婴儿恶性游走性部分性发作是一种癫痫综合征,其特征为发病年龄在 6 个月之前,发作为多灶性,脑电图表现为来自两个半球的独立和顺序出现的发作。本文描述了一例该综合征 4 个月大男婴的临床经过,同时提供了发作和脑电图记录的视频资料。讨论了癫痫样活动从一个半球到另一个半球交替或“游走”的可能神经生理学机制。