Hospital of Leverkusen, Department of Pediatrics, 51375 Leverkusen, Germany.
J Nutr. 2011 Jul;141(7):1348-54. doi: 10.3945/jn.110.137000. Epub 2011 May 11.
Dietary factors, especially during early childhood, have been discussed as potentially critical for the development of childhood overweight. This study evaluated associations between added sugar intake during early childhood and BMI and body fat at age 7 y. Analysis was based on data from 216 participants of the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) Study. Life-course plots were constructed to evaluate the association between added sugar intake at different ages (0.5, 1, 1.5, and 2 y) and BMI SD score (BMI-SDS) and % body fat (%BF) at age 7 y. Multivariable analyses were performed for the periods identified as critical for later BMI and body fat. Added sugar intake at age 1 y and the change in intake levels during the second year of life emerged as potentially critical. At age 1 y, a higher total added sugar intake was related to a lower BMI-SDS at age 7 y [adjusted β ± SE: -0.116 ± 0.057 BMI-SDS/percent energy (%En) added sugar; P = 0.04]. Conversely, an increase in total added sugar in the second year of life (Δ%En between age 1 and 2 y) tended to be associated with a higher BMI-SDS (adjusted β ± SE: 0.074 ± 0.043 BMI-SDS/Δ%En added sugar; P = 0.09). No associations were observed with %BF. In conclusion, added sugar intake at low intake levels during early childhood does not appear to be critical for BMI and body fat at age 7 y. However, detrimental effects on BMI development may emerge when added sugar intakes are increased to higher levels.
饮食因素，尤其是在儿童早期，被认为是儿童超重发展的关键因素。本研究评估了儿童早期添加糖摄入量与 7 岁时 BMI 和体脂肪的关系。分析基于多特蒙德营养和人体测量纵向设计（DONALD）研究的 216 名参与者的数据。生命历程图用于评估不同年龄（0.5、1、1.5 和 2 岁）添加糖摄入量与 7 岁时 BMI 标准差评分（BMI-SDS）和体脂肪百分比（%BF）之间的关系。对于被认为与后期 BMI 和体脂肪相关的时期，进行了多变量分析。1 岁时的添加糖摄入量和生命第二年摄入量的变化被认为是潜在的关键因素。1 岁时，较高的总添加糖摄入量与 7 岁时较低的 BMI-SDS 相关[调整后的 β ± SE：-0.116 ± 0.057 BMI-SDS/能量百分比（%En）添加糖；P = 0.04]。相反，生命第二年总添加糖的增加（1 岁至 2 岁之间的Δ%En）与 BMI-SDS 升高相关（调整后的 β ± SE：0.074 ± 0.043 BMI-SDS/Δ%En 添加糖；P = 0.09）。与 %BF 没有关联。总之，儿童早期低摄入量的添加糖摄入量似乎不会对 7 岁时的 BMI 和体脂肪产生影响。然而，当添加糖摄入量增加到较高水平时，可能会对 BMI 的发展产生不利影响。
