Rüth S, Spatz J, Anthuber M
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Klinikum Augsburg, Deutschland.
Chirurg. 2011 Jun;82(6):520-5. doi: 10.1007/s00104-010-2062-8.
The knowledge that due to the adenoma-cancer sequence polyps will develop sooner or later into invasive cancer demands the complete removal of colorectal polyps. The majority of polyps can be endoscopically removed. The indications for surgical removal of polyps are a previous incomplete endoscopic resection, location not amenable to endoscopic removal and lesions which are macroscopically highly suspicious for malignancy and cannot be detached by submucosal saline injection. If a surgical approach is indicated minimally invasive surgery in the hands of an experienced laparoscopic surgeon is a suitable option. Adenomas suspicious for malignancy in the lower two thirds of the rectum should not be treated by time-consuming endoscopic submucosal dissection (ESD) and can be quickly and safely removed transanally, conventionally or by transanal endoscopic microsurgery (TEM) by a full thickness én bloc resection. This allows the pathologist to determine the depth of invasion and the completeness of resection in terms of the circumferential margin and a definitive radical surgical approach is only necessary in high risk situations.
由于腺瘤-癌序列,息肉迟早会发展为浸润性癌,这一认识要求彻底切除结直肠息肉。大多数息肉可通过内镜切除。息肉手术切除的指征包括既往内镜切除不完全、位置不适合内镜切除以及肉眼高度怀疑为恶性且不能通过黏膜下注射生理盐水分离的病变。如果需要手术治疗,由经验丰富的腹腔镜外科医生进行的微创手术是一个合适的选择。直肠下三分之二处怀疑为恶性的腺瘤不应采用耗时的内镜黏膜下剥离术(ESD)治疗,可通过传统经肛门或经肛门内镜显微手术(TEM)进行全层整块切除,快速且安全地经肛门切除。这能让病理学家确定浸润深度以及切缘的切除完整性,只有在高风险情况下才需要采取确定性的根治性手术方法。