Department of Psychology, Ohio University, Athens, OH, USA.
Ann Behav Med. 2011 Oct;42(2):153-73. doi: 10.1007/s12160-011-9274-0.
Acute psychological stress can produce significant hemoconcentration as well as prothrombotic changes in blood, both of which may have potentially harmful effects on the cardiovascular system. It is unclear whether these effects are independent or have influence on each other.
This review discusses research investigating the effects of acute psychological stress on hemoconcentration and hemostasis and explores future directions for psychohematology research. Physiology, associations with cardiovascular disease, and relationships between acute psychological stress are discussed independently for hemoconcentration and hemostasis, followed by an examination of the effects of stress-hemoconcentration on hemostasis.
Traditional methods of adjusting for stress-hemoconcentration effects (e.g., calculated plasma volume or hematocrit level corrections) may not be appropriate when examining stress-induced changes in hemostasis. The effects of acute stress on hemostasis should be examined in conjunction with hemoconcentration.
急性心理应激可导致血液明显的浓缩和促血栓形成改变，这两者都可能对心血管系统产生潜在的有害影响。目前尚不清楚这些影响是否相互独立或相互影响。
本综述讨论了急性心理应激对血液浓缩和止血的影响，并探讨了心理血液学研究的未来方向。本文分别讨论了血液浓缩和止血的生理学、与心血管疾病的关联以及急性心理应激之间的关系，然后研究了应激-血液浓缩对止血的影响。
在检查应激引起的止血变化时，传统的用于调整应激-血液浓缩影响的方法（例如，计算的血浆体积或红细胞压积水平校正）可能并不合适。应将急性应激对止血的影响与血液浓缩结合起来进行检查。
