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特定农药、药物及化学品的毒理学。抗凝血剂、胆钙化醇及溴敌隆类灭鼠剂。

Toxicology of selected pesticides, drugs, and chemicals. Anticoagulant, cholecalciferol, and bromethalin-based rodenticides.

作者信息

Dorman D C

机构信息

Department of Veterinary Biosciences, University of Illinois, Urbana-Champaign College of Veterinary Medicine.

出版信息

Vet Clin North Am Small Anim Pract. 1990 Mar;20(2):339-52. doi: 10.1016/s0195-5616(90)50028-5.

DOI:10.1016/s0195-5616(90)50028-5
PMID:2156370
Abstract

The control of rodent pests is a continuing goal of mankind. To this end, a multitude of rodenticides have been produced, each designed to kill rodents by exerting their toxic effects on various body systems. As examples, veterinarians have had to manage companion animal poisonings due to anticoagulant, sodium fluoroacetate (compound 1080), thallium, barium carbonate, and zinc phosphide-based rodenticides. Many of these rodenticides were introduced because of their anticipated safety in relation to nontarget species; unfortunately, this has not been the case. Veterinarians must attempt to identify the specific rodenticide involved in poisoning cases. Therapeutic success in these poisonings is often more dependent upon symptomatic and supportive care rather than the use of antidotal therapy.

摘要

控制啮齿动物害虫是人类的一个持续目标。为此,已生产出大量灭鼠剂,每种灭鼠剂都旨在通过对各种身体系统施加毒性作用来杀死啮齿动物。例如,兽医不得不处理因抗凝血剂、氟乙酸钠(1080 化合物)、铊、碳酸钡和磷化锌基灭鼠剂导致的伴侣动物中毒事件。许多这类灭鼠剂因其预期对非目标物种的安全性而被引入;不幸的是,实际情况并非如此。兽医必须尝试确定中毒病例中涉及的具体灭鼠剂。这些中毒病例的治疗成功往往更多地依赖于对症和支持性护理,而非使用解毒疗法。

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