Arnold and Mabel Beckman Laboratory of Chemical Synthesis, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.
J Am Chem Soc. 2011 Jun 8;133(22):8525-7. doi: 10.1021/ja202818v. Epub 2011 May 12.
We report the development of ruthenium-based metathesis catalysts with chelating N-heterocyclic carbene (NHC) ligands that catalyze highly Z-selective olefin metathesis. A very simple and convenient procedure for the synthesis of such catalysts has been developed. Intramolecular C-H bond activation of the NHC ligand, promoted by anion ligand substitution, forms the appropriate chelate for stereocontrolled olefin metathesis.
我们报告了具有螯合 N-杂环卡宾（NHC）配体的钌基复分解催化剂的开发，该催化剂能够催化高度 Z 选择性的烯烃复分解。已经开发出一种非常简单方便的合成此类催化剂的方法。阴离子配体取代促进 NHC 配体的分子内 C-H 键活化，形成适合立体控制烯烃复分解的螯合物。
