Wolff H, Ridwelski K, Lorf T
Klinik für Chirurgie, des Bereichs Medizin (Charité), Humboldt-Universität zu Berlin.
Zentralbl Chir. 1990;115(1):1-14.
Seventy-nine patients with extrahepatic malignant cholangiocarcinomas were treated at the Surgical Clinic of the Charité from 1981 to 1989. Thirty-two of these patients suffered from Klatskin tumour. Exact preoperative staging includes sonography, CT scan, cholangiography (PTC or ERCP). Angiography can help to clear the diagnoses. Sixteen patients were considered inoperable. The therapy was surgical bypass, surgically or percutaneously placed catheters and endoscopically placed endoprostheses, a median survival time was 2 to 6 months. The other 16 patients underwent 12 resections and four liver transplantations. Two of these transplanted patients are still tumour-free, their survival times ranging from 2 to 6 years. The median survival time of the patients undergoing resection amounts to 22 months and operation mortality, 12%. Optimal treatment strategies by the Klatskin tumours is the radical resection.
1981年至1989年期间，79例肝外恶性胆管癌患者在夏里特外科诊所接受了治疗。其中32例患者患有肝门部胆管癌。精确的术前分期包括超声检查、CT扫描、胆管造影（经皮肝穿刺胆管造影术或内镜逆行胰胆管造影术）。血管造影有助于明确诊断。16例患者被认为无法手术。治疗方法为手术旁路、手术或经皮放置导管以及内镜放置内支架，中位生存时间为2至6个月。另外16例患者接受了12次切除术和4次肝移植。其中2例移植患者仍无肿瘤，其生存时间为2至6年。接受切除术患者的中位生存时间为22个月，手术死亡率为12%。肝门部胆管癌的最佳治疗策略是根治性切除。
