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[宫颈癌癌前病变及早期阶段的超微结构乳头瘤病毒检测]

[Ultrastructural papilloma virus detection in precancerous and early stages of cervix cancer].

作者信息

Barten G

机构信息

Klinik für Gynäkologie und Geburtshilfe, Bereichs Medizin der Wilhelm-Pieck-Universität Rostock.

出版信息

Zentralbl Gynakol. 1990;112(1):33-8.

PMID:2156396
Abstract

100 women with pathologic findings in the uterine cervix are the basis of this study. To assess papilloma virus articles methods of electron microscopy have been used in specimens of 59 women if koilocytes were present. Inside the nucleus of koilocytes in 51 cases virus particles could be detected, in 31 cases isolated and in 20 cases agglomerated between the chromatin. In all 10 condylomas without nuclear atypia we could assess virus particles. With increasing atypia the detection of papilloma virus decreases.

摘要

100例子宫颈有病理检查结果的女性是本研究的基础。为评估乳头瘤病毒,若存在挖空细胞,则对59例女性的标本采用了电子显微镜检查方法。在51例挖空细胞核内可检测到病毒颗粒,31例为单个病毒颗粒,20例为聚集于染色质之间的病毒颗粒。在所有10例无核异型性的尖锐湿疣中均可评估到病毒颗粒。随着异型性增加,乳头瘤病毒的检测率降低。

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Zentralbl Gynakol. 1990;112(1):33-8.
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