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[子宫阴道部乳头瘤病毒(HPV)相关改变的形态学评估及临床意义]

[Morphologic evaluation and clinical significance of papillomavirus (HPV)-associated changes in the portio vaginalis uteri].

作者信息

Förster G, Rosenkranz M

机构信息

Klinik für Gynäkologie und Geburtshilfe, Bereiches Medizin der Karl-Marx-Universität Leipzig, DDR.

出版信息

Zentralbl Allg Pathol. 1987;133(6):543-50.

PMID:2833052
Abstract

HPV-induced changes in the portio vaginalis uteri can and have lead to misinterpretations since they frequently occur in combination with or resemble precancerous or cancerous changes. The morphological peculiarities and growth patterns of koilocytotic changes in the portio vaginalis uteri are described. Among 684 conizations performed, 169 (24.7%) were found to have features of an HPV-infection. Of these, 75.7% also had preneoplastic or neoplastic changes. Review of the cytological findings revealed that in 66.7% of the cases with histologically verified koilocytosis a false positive finding of malignancy had been recorded.

摘要

人乳头瘤病毒(HPV)引起的子宫阴道部变化可能且已经导致了错误解读,因为它们经常与癌前或癌性变化同时出现或相似。本文描述了子宫阴道部挖空细胞变化的形态学特征和生长模式。在684例宫颈锥切术中,发现169例(24.7%)具有HPV感染特征。其中,75.7%还伴有癌前或癌性变化。对细胞学检查结果的回顾显示,在组织学证实为挖空细胞的病例中,66.7%曾记录有恶性肿瘤的假阳性结果。

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