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血液系统恶性肿瘤患者的生育力保存。

Preservation of fertility in females with haematological malignancy.

机构信息

Department of Gynecology, Université Catholique de Louvain, Brussels, Belgium.

出版信息

Br J Haematol. 2011 Jul;154(2):175-84. doi: 10.1111/j.1365-2141.2011.08723.x. Epub 2011 May 12.

Abstract

Several options are currently available for the preservation of fertility in cancer patients: embryo cryopreservation, oocyte cryopreservation or ovarian tissue cryopreservation. The choice of the most suitable strategy for preserving fertility depends on different parameters: the type and timing of chemotherapy, the type of cancer, the patient's age and the partner status. Cryopreservation of ovarian tissue is the only option available for prepubertal girls and woman who cannot delay the start of chemotherapy. So far, 15 live births have been obtained after orthotopic transplantation of cryopreserved ovarian tissue.

摘要

目前有几种选择可用于保存癌症患者的生育能力

胚胎冷冻保存、卵母细胞冷冻保存或卵巢组织冷冻保存。选择最适合的生育力保存策略取决于不同的参数:化疗的类型和时间、癌症的类型、患者的年龄和伴侣状况。卵巢组织冷冻保存是青春期前女孩和不能延迟化疗开始的女性唯一可用的选择。迄今为止,在进行冷冻保存的卵巢组织原位移植后已经获得了 15 例活产。

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