Yoshino Kazuho, Nishiumi Noboru, Masuda Ryota, Saito Yuki, Tokuda Yutaka, Iwazaki Masayuki
Division of General Thoracic Surgery, Dept. of Surgery, Tokai University School of Medicine.
Gan To Kagaku Ryoho. 2011 May;38(5):803-6.
Many cancer patients suffer from rapidly-progressing dyspnea that is difficult to relieve.
The subjects were 26 patients who had dyspnea that was difficult to relieve. The Numeric Rating Scale was used to evaluate their dyspnea. For all patients, the cause of the dyspnea was investigated by CT and x-rays.
The principal causes of the dyspnea were pleural effusion that increased daily, complications from pneumonia, massive ascites, multiple metastatic lung tumors and atelectasis, recurrent laryngeal nerve paralysis and narrowing secondary airway compression. Dyspnea was caused by a variety of conditions that overlapped over time, intensifying patients' discomfort. Among 14 patients for whom we recommended treatment with sedation, only 8 of them consented. Among the patients who were treated with sedation, the median interval between the exacerbation of dyspnea and death was 16 days; among non-sedated patients it was 18 days.
Palliative care physicians who specialize in the respiratory system can, to some extent, predict the occurrence of rapidly progressive dyspnea in cancer patients. It is important to explain the methods of relieving dyspnea to the patient, the patient's family, and the oncologist early, so that decisions on how to manage dyspnea can be made in advance.
许多癌症患者患有难以缓解的快速进展性呼吸困难。
研究对象为26例难以缓解呼吸困难的患者。采用数字评分量表评估其呼吸困难情况。对所有患者,通过CT和X线检查呼吸困难的原因。
呼吸困难的主要原因是每日增多的胸腔积液、肺炎并发症、大量腹水、多发性肺转移瘤和肺不张、喉返神经麻痹以及继发性气道受压狭窄。呼吸困难由多种情况随时间重叠导致,加剧了患者的不适。在我们建议进行镇静治疗的14例患者中,只有8例同意。在接受镇静治疗的患者中,呼吸困难加重至死亡的中位间隔时间为16天;未接受镇静治疗的患者为18天。
专门从事呼吸系统疾病治疗的姑息治疗医生在一定程度上可以预测癌症患者快速进展性呼吸困难的发生。尽早向患者、患者家属和肿瘤学家解释缓解呼吸困难的方法很重要,以便能提前做出如何处理呼吸困难的决策。