一种用于健康状况测量和临床管理的多属性方法，以儿童脑肿瘤应用为例进行说明。

A multiattribute approach to health-status measurement and clinical management illustrated by an application to brain-tumors in childhood.

作者信息

Barr R, Pai M, Weitzman S, Feeny D, Furlong W, Rosenbaum P, Torrance G

机构信息

MCMASTER UNIV,DEPT ECON,HAMILTON L8N 3Z5,ONTARIO,CANADA. MCMASTER UNIV,DEPT CLIN EPIDEMIOL & BIOSTAT,HAMILTON L8N 3Z5,ONTARIO,CANADA. MCMASTER UNIV,CTR HLTH ECON & POLICY ANAL,HAMILTON L8N 3Z5,ONTARIO,CANADA. HOSP SICK CHILDREN,TORONTO M5G 1X8,ONTARIO,CANADA. CHILDRENS HOSP CHEDOKE MCMASTER,HAMILTON,ON,CANADA.

出版信息

Int J Oncol. 1994 Mar;4(3):639-48. doi: 10.3892/ijo.4.3.639.

DOI:10.3892/ijo.4.3.639

PMID:21566971

Abstract

A comprehensive multi-attribute system was devised to assess global morbidity burden. The system was used to obtain qualitative and quantitative measures of health-status for a case series of survivors of brain tumors in childhood. Health-related quality-of-life scores for each global health-state were calculated from a utility function derived from measures of preferences collected during surveys of a random sample of parents of school age children in the general public (n=194). Global multi-attribute health status (MAHS) utility scores revealed a wide range of severity in morbidity burden. We suggest that the assessment of health-related quality-of-life should become an integral part of clinical management.

摘要

设计了一个综合多属性系统来评估全球疾病负担。该系统用于获取一组儿童脑肿瘤幸存者的健康状况的定性和定量指标。每个总体健康状态的健康相关生活质量得分是根据一个效用函数计算得出的，该效用函数源自对普通公众中随机抽取的学龄儿童家长样本（n = 194）进行调查时收集的偏好测量值。全球多属性健康状况（MAHS）效用得分显示疾病负担的严重程度范围很广。我们建议，与健康相关的生活质量评估应成为临床管理的一个组成部分。