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高度近视性板层黄斑裂孔的自然病程。

Natural history of lamellar macular holes in highly myopic eyes.

机构信息

Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

Am J Ophthalmol. 2011 Jul;152(1):96-99.e1. doi: 10.1016/j.ajo.2011.01.021. Epub 2011 May 12.

Abstract

PURPOSE

To determine the natural course of lamellar macular holes (MHs) in highly myopic eyes.

DESIGN

Prospective and observational case series.

METHODS

Twenty-four eyes of 21 consecutive patients with a lamellar MH and high myopia (myopic refractive error >8 diopters or axial length ≥26.5 mm) were followed for ≥12 months. The changes of the optical coherence tomography (OCT) findings and the best-corrected visual acuity (BCVA) were analyzed. The progression of the lamellar MH to a full-thickness MH and the change of the BCVA were analyzed.

RESULTS

At the initial examination, an epiretinal membrane was identified by OCT in 17 of the 24 eyes (70.8%) and 7 eyes (29.2%) had macular retinoschisis. Twenty-three of 24 eyes (95.8%) did not show any changes of the lamellar MH in the OCT images during a mean follow-up of 19.2 ± 10.2 months. However, the remaining eye progressed to a full-thickness MH and pars plana vitrectomy was required to close the MH. Except for this 1 eye, the BCVA was maintained (within 0.2 logMAR change) during the follow-up period of at least 1 year.

CONCLUSIONS

A lamellar MH in highly myopic eyes is a relatively stable condition.

摘要

目的

确定高度近视眼中板层黄斑裂孔(MH)的自然病程。

设计

前瞻性和观察性病例系列。

方法

对 21 例连续伴有板层 MH 和高度近视(近视屈光不正>8 屈光度或眼轴长度≥26.5 毫米)的患者的 24 只眼进行了≥12 个月的随访。分析了光学相干断层扫描(OCT)检查结果和最佳矫正视力(BCVA)的变化。分析了板层 MH 向全层 MH 的进展以及 BCVA 的变化。

结果

在初始检查时,24 只眼中的 17 只(70.8%)通过 OCT 识别出了视网膜前膜,7 只眼(29.2%)有黄斑劈裂。在平均 19.2±10.2 个月的随访中,24 只眼中的 23 只(95.8%)的板层 MH 在 OCT 图像中没有任何变化。然而,剩下的一只眼进展为全层 MH,需要进行扁平部玻璃体切除术来封闭 MH。除了这 1 只眼外,在至少 1 年的随访期间,BCVA 保持不变(0.2 logMAR 变化范围内)。

结论

高度近视眼中的板层 MH 是一种相对稳定的情况。

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