氯胺酮-HC1麻醉在大鼠乳糜微粒-甘油三酯代谢研究中的应用。
Use of ketamine-HC1 anesthesia in studies of chylomicron-triglyceride metabolism in the rat.
作者信息
Brown C M, Layman D K
机构信息
Division of Foods and Nutrition, University of Illinois, Urbana-Champaign 61801.
出版信息
Lab Anim Sci. 1990 Mar;40(2):183-5.
PMID:2157100
Abstract
Ketamine with 10% acepromazine (Km/Ac) was evaluated for use in an investigation of plasma chylomicron-triglyceride clearance in rats. Clearance rate and the half-life of radiolabeled (14C) chylomicron triglycerides plus tissue uptake of 14C-fatty acids were equal in Km/Ac anesthetized and non-anesthetized rats. Km/Ac was found to be a suitable anesthesia in rats for the study of plasma chylomicron-triglyceride clearance.
摘要
评估了氯胺酮与10%乙酰丙嗪（Km/Ac）在大鼠血浆乳糜微粒甘油三酯清除率研究中的应用。在Km/Ac麻醉和未麻醉的大鼠中，放射性标记（14C）的乳糜微粒甘油三酯的清除率和半衰期以及14C-脂肪酸的组织摄取量是相等的。发现Km/Ac是用于大鼠血浆乳糜微粒甘油三酯清除率研究的合适麻醉剂。
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