Okushi Tetsushi, Yoshikawa Mamoru, Otori Nobuyoshi, Matsuwaki Yoshinori, Asaka Daiya, Nakayama Tsugihisa, Morimoto Tadamitsu, Moriyama Hiroshi
Department of Otorhinolaryngology, Jikei University School of Medicine, 3-25-8, Nishishinbashi, Minato-ku, Tokyo, 105-8461, Japan.
Auris Nasus Larynx. 2012 Feb;39(1):31-7. doi: 10.1016/j.anl.2011.02.008. Epub 2011 May 14.
Nasal packing is used to control postoperative bleeding and wound healing, and it also exerts a very strong influence on the comfort of the patient. Sorbsan(®) (calcium alginate) is an absorbent packing that shows a potent hemostatic effect and is able to maintain wound surfaces in a moist environment by absorbing and gelling the wound exudate. The aim of this study was to evaluate the early symptoms and QOL with Sorbsan(®) versus Beschitin-F(®) (chitin-coated gauze) for middle meatus packing after endoscopic sinus surgery (ESS).
We performed a cohort study of 40 patients who underwent ESS. Following ESS, the patients were randomly allocated into two groups of 20 patients each who underwent insertion of either Sorbsan(®) or Beschitin-F(®) into the middle meatus. A daily diary was used to record the symptoms and QOL, measured using visual analogue scales, before the ESS and on each day thereafter. Postoperative bleeding and local infection were also recorded.
The scores for each of the symptoms of nasal pain, headache, nasal bleeding and postnasal drip were statistically significantly lower in the Sorbsan(®) group. The scores for each of the QOL parameters, including the effect on their stay in the hospital and sleep disturbance, were also significantly lower in the Sorbsan(®) group. There were no findings of postoperative hemorrhage or local infection in either group.
Sorbsan(®) packing did not cause any major complications and has the potential to reduce nasal pain and suffering in post ESS patients compared with gauze packing.
鼻腔填塞用于控制术后出血和促进伤口愈合，对患者舒适度也有很大影响。索布森（Sorbsan®）（藻酸钙）是一种具有强大止血作用的吸收性填塞物，能够通过吸收和凝胶化伤口渗出液使伤口表面保持湿润环境。本研究旨在评估在内镜鼻窦手术（ESS）后中鼻道填塞中，使用索布森（Sorbsan®）与贝西丁 - F（Beschitin - F®）（几丁质涂层纱布）的早期症状和生活质量。
我们对40例行ESS的患者进行了队列研究。ESS后，将患者随机分为两组，每组20例，分别在中鼻道插入索布森（Sorbsan®）或贝西丁 - F（Beschitin - F®）。使用每日日记记录ESS前及此后每天的症状和生活质量，采用视觉模拟量表进行测量。还记录了术后出血和局部感染情况。
索布森（Sorbsan®）组的鼻痛、头痛、鼻出血和鼻后滴漏等各项症状评分在统计学上显著更低。索布森（Sorbsan®）组的各项生活质量参数评分，包括对住院时间和睡眠障碍的影响，也显著更低。两组均未发现术后出血或局部感染情况。
与纱布填塞相比，索布森（Sorbsan®）填塞未引起任何重大并发症，并且有可能减轻ESS术后患者的鼻痛和痛苦。
