Nikolaou Panagiota, Papoutsis Ioannis, Stefanidou Maria, Dona Artemis, Maravelias Constantinos, Spiliopoulou Chara, Athanaselis Sotirios
Department of Forensic Medicine and Toxicology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
J Emerg Med. 2012 Jun;42(6):662-5. doi: 10.1016/j.jemermed.2011.03.023. Epub 2011 May 14.
A large number of plants, seeds, and berries have been used for medicinal, psychotropic, or aphrodisiac purposes for a thousand years. Mandragora officinarum belongs to the family of Solanaceae and is traditionally known as an aphrodisiac and is closely associated with witchcraft.
In this study we report a case of an accidental poisoning after ingestion of some "aphrodisiac" berries and the contribution of the toxicological analysis in the case investigation.
A 35-year-old man was admitted to the hospital with clinical signs and symptoms of an anticholinergic syndrome. The diagnosis of the poisoning was made by the toxicological analysis of the patient's urine. The cause of the poisoning was revealed by his girlfriend's disclosure that the patient had intentionally consumed some "aphrodisiac" berries to enhance his sexual performance. Subsequently, berries similar to the ones consumed were sent to the laboratory. The analysis of the urine and the berries revealed the presence of hyoscyamine and scopolamine; the berries were identified as Mandragora officinarum berries. Decontamination and symptomatic treatment were proven effective for the control of this poisoning. The patient recovered completely after hospitalization for 4 days.
This case report indicates the importance of analytical toxicology in diagnosis of intoxications after the consumption of unknown plants or plant products and presents the clinical aspects of Mandragora intoxication.
大量植物、种子和浆果已被用于药用、精神作用或壮阳目的达千年之久。药用茄参属于茄科，传统上被认为是一种壮阳药，且与巫术密切相关。
在本研究中，我们报告了一例因误食一些“壮阳”浆果导致意外中毒的病例以及毒理学分析在该病例调查中的作用。
一名35岁男性因抗胆碱能综合征的临床症状和体征入院。通过对患者尿液进行毒理学分析做出中毒诊断。其女友透露患者为增强性功能故意食用了一些“壮阳”浆果，由此揭示了中毒原因。随后，将与所食用浆果类似的样本送至实验室。对尿液和浆果的分析显示存在莨菪碱和东莨菪碱；这些浆果被鉴定为药用茄参的浆果。去污和对症治疗被证明对控制此次中毒有效。患者住院4天后完全康复。
本病例报告表明分析毒理学在诊断食用未知植物或植物产品后中毒方面的重要性，并呈现了药用茄参中毒的临床情况。
