De Salvo R, Sinardi A U, Santamaria L B, Carfì V, Spada A, Praticò C, Falcone M
Minerva Anestesiol. 1980 Dec;46(12):1265-72.
After mentioning the botanic characteristics of mandragora, its territorial distribution, morphological characteristics and the toxicological properties of its alkaloids, a clinical case of accidental mandragora poisoning is reported. The case was successfully treated with atropinic block antagonists, namely cholinesterase inhibitors. Apart from its serious symptomatology, mandragora poisoning also involves considerable metabolic commitment of liver and kidney, which present evident signs of disturbance. Information about these and other insidious plants should be spread to prevent such cases of poisoning, whose gravity is enhanced by the fact that they are exceptional and not often encountered in clinical practice.
在提及了曼陀罗的植物学特征、地域分布、形态特征及其生物碱的毒理学特性后,报告了一例曼陀罗意外中毒的临床病例。该病例通过使用阿托品阻断拮抗剂即胆碱酯酶抑制剂成功治愈。除了严重的症状外,曼陀罗中毒还涉及肝脏和肾脏相当大的代谢负担,它们呈现出明显的功能紊乱迹象。关于这些以及其他潜在危险植物的信息应予以传播,以防止此类中毒事件的发生,由于它们很罕见且在临床实践中不常遇到,所以这类中毒事件的严重性更甚。