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并行放置第二根支架以治疗恶性输尿管梗阻中难治性输尿管支架功能障碍。

Parallel second stent placement for refractory ureteral stent malfunction in malignant ureteral obstruction.

机构信息

Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan.

出版信息

J Vasc Interv Radiol. 2011 Jul;22(7):1012-6. doi: 10.1016/j.jvir.2011.02.038. Epub 2011 May 14.

Abstract

PURPOSE

To review retrospectively the outcome of placement of a parallel second ureteral stent in patients with urinary obstruction secondary to a malignancy.

MATERIALS AND METHODS

During the period 2005-2008, the medical records of patients with ureteral obstruction from an abdominal malignancy were reviewed. Patients who experienced malfunction of the first ureteral stent subsequently underwent either initial stent exchange (control group) or a parallel second ureteral stent placement. The outcomes of both groups were evaluated in terms of stent function at 1 week, 1 month, and 3 months after the procedure. Several clinical and imaging parameters were also compared between the two groups.

RESULTS

The stent malfunction rate increased more rapidly in the control group. In 1 week, the malfunction rate was 29.4% in the parallel ureteral stent group and 56.7% in the control group. By the end of the third month, the malfunction rate was 72.7% in the parallel ureteral stent group and 100% in the control group. The creatinine level after the procedure was significantly lower in the parallel ureteral stent group (P = 0.004). The incidence of symptomatic urinary tract infection (UTI) was around 30% in both groups (P = 1.000).

CONCLUSIONS

Parallel second ureteral stent placement has a high technical success rate. For terminally ill patients who have a malignancy and an occluded ureteral stent, the technique can effectively relieve obstruction and prolong the function of the stent.

摘要

目的

回顾性分析因恶性肿瘤导致尿路梗阻患者并行留置双输尿管支架治疗的效果。

材料与方法

回顾 2005 年至 2008 年因输尿管梗阻接受治疗的腹部恶性肿瘤患者的病历资料。因第一根输尿管支架发生故障而接受治疗的患者,随机分为初始支架更换组(对照组)或并行留置双输尿管支架组。评估两组患者术后 1 周、1 个月和 3 个月的支架功能,并比较两组的临床和影像学参数。

结果

对照组的支架故障发生率增加更快。术后 1 周,并行输尿管支架组的故障发生率为 29.4%,对照组为 56.7%;术后 3 个月,并行输尿管支架组的故障发生率为 72.7%,对照组为 100%。并行输尿管支架组术后肌酐水平显著低于对照组(P = 0.004)。两组患者均有 30%左右发生有症状的尿路感染(UTI)(P = 1.000)。

结论

并行留置双输尿管支架技术成功率高。对于患有恶性肿瘤且输尿管支架阻塞的终末期患者,该技术可有效缓解梗阻并延长支架功能。

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