系统性硬化症患者循环中白细胞介素33水平升高与疾病早期阶段及微血管受累相关。 - Suppr

Increased circulating levels of interleukin 33 in systemic sclerosis correlate with early disease stage and microvascular involvement.

作者信息

Manetti Mirko, Guiducci Serena, Ceccarelli Claudia, Romano Eloisa, Bellando-Randone Silvia, Conforti Maria Letizia, Ibba-Manneschi Lidia, Matucci-Cerinic Marco

出版信息

Ann Rheum Dis. 2011 Oct;70(10):1876-8. doi: 10.1136/ard.2010.148247. Epub 2011 May 12.

DOI:10.1136/ard.2010.148247

PMID:21571732

Abstract

摘要

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Increased circulating levels of interleukin 33 in systemic sclerosis correlate with early disease stage and microvascular involvement.系统性硬化症患者循环中白细胞介素33水平升高与疾病早期阶段及微血管受累相关。

Ann Rheum Dis. 2011 Oct;70(10):1876-8. doi: 10.1136/ard.2010.148247. Epub 2011 May 12.

Increased serum IL-33 levels may indicate vascular involvement in systemic sclerosis.血清白细胞介素-33水平升高可能表明系统性硬化症存在血管受累情况。

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Interleukin-17 and interleukin-23: importance in the pathogenesis of lung impairment in patients with systemic sclerosis.白细胞介素-17与白细胞介素-23：在系统性硬化症患者肺损伤发病机制中的重要性

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Serum IL-33 levels are raised in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis.血清 IL-33 水平在系统性硬化症患者中升高：与皮肤硬化程度和肺纤维化严重程度相关。

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Higher levels of serum interleukin-35 are associated with the severity of pulmonary fibrosis and Th2 responses in patients with systemic sclerosis.血清白细胞介素-35 水平升高与系统性硬化症患者肺纤维化的严重程度和 Th2 反应相关。

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Serum interleukin-34 levels in patients with systemic sclerosis: Clinical association with interstitial lung disease.系统性硬化症患者血清白细胞介素-34 水平：与间质性肺病的临床相关性。

J Dermatol. 2018 Oct;45(10):1216-1220. doi: 10.1111/1346-8138.14538. Epub 2018 Jul 13.

Early systemic sclerosis: serum profiling of factors involved in endothelial, T-cell, and fibroblast interplay is marked by elevated interleukin-33 levels.早期系统性硬化症：参与内皮细胞、T细胞和成纤维细胞相互作用的因子的血清分析显示白细胞介素-33水平升高。

J Clin Immunol. 2014 Aug;34(6):663-8. doi: 10.1007/s10875-014-0037-0. Epub 2014 Apr 24.

Increased IL-35 serum levels in systemic sclerosis and association with pulmonary interstitial involvement.系统性硬化症患者血清IL-35水平升高及其与肺间质受累的关系。

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Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease.在系统性硬化症中，除了 Th17 和 Th2 淋巴细胞外，循环 Th22 的频率增加：与间质性肺病有关。

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Elevated Interleukin-21 expression is correlated with systemic sclerosis' severity in Tunisian patients.白细胞介素-21表达升高与突尼斯患者系统性硬化症的严重程度相关。

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Increased circulating levels of interleukin 33 in systemic sclerosis correlate with early disease stage and microvascular involvement.

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