Huppert P E, Duda S H, Haase K K, Karsch K R, Claussen C D
Abt. für Radiologische Diagnostik, Eberhard-Karls-Universität Tübingen.
Rofo. 1990 Mar;152(3):259-63. doi: 10.1055/s-2008-1046865.
First clinical experiences in the treatment of chronically occluded arteries with 7F-multi-fiber catheter systems transmitting pulsed laser light are presented. 16 patients (7 stadium IIb, 4 stadium III, 5 stadium IVa Fontain) underwent the procedure. 14 of 16 lesions (distance: 0.5-10 cm), most of them with visible calcification, could be recanalized successfully. After the catheter had passed lesions several times, remaining stenoses of 48% (mean value) could be reduced by balloon angioplasty. By moving the catheter with less speed than the experimentally determined speed of laser light ablation and by guiding it over a safety wire, perforation and embolization could be avoided. In one case, occlusion material was pressed into collateral vessels and in two cases groin hematomas had to be observed.
本文介绍了使用传输脉冲激光的7F多光纤导管系统治疗慢性闭塞动脉的首次临床经验。16例患者（7例IIb期、4例III期、5例Fontain IVa期）接受了该手术。16处病变中的14处（长度为0.5 - 10厘米），其中大部分可见钙化，均成功实现再通。在导管多次穿过病变部位后，通过球囊血管成形术可将剩余48%（平均值）的狭窄程度降低。通过以低于实验确定的激光消融速度移动导管并在安全导丝引导下操作，可避免穿孔和栓塞。有1例患者，闭塞物质被压入侧支血管，还有2例患者出现腹股沟血肿需要观察。
